Team:Goettingen/project overview/project drylab results
From 2014.igem.org
Project
Dry lab
Results summary:
We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.
Peptide
PNG*
PDB
Peptide location
QMEAN score
Overall DOPE score
Energy profile
Prey 3
Download
K17-E42
0.512
-7053.966797
Download
Prey 4.1
Download
K17-E44
0.468
-7246.956055
Download
Prey 5
Download
K17-E44
0.495
-7501.071777
Download
Prey 13
Download
K17-E42
0.535
-7729.056152
Download
Prey 15
Download
K17-E42
0.447
-7671.660156
Download
*The peptide is shown in red and the scaffold in blue.
This is peptide IGP4 that shows interaction with ssr1 protein from Candida glabrata
We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.
Peptide | PNG* | PDB | Peptide location | QMEAN score | Overall DOPE score | Energy profile |
Prey 3 | Download | K17-E42 | 0.512 | -7053.966797 | Download | |
Prey 4.1 | Download | K17-E44 | 0.468 | -7246.956055 | Download | |
Prey 5 | Download | K17-E44 | 0.495 | -7501.071777 | Download | |
Prey 13 | Download | K17-E42 | 0.535 | -7729.056152 | Download | |
Prey 15 | Download | K17-E42 | 0.447 | -7671.660156 | Download |
*The peptide is shown in red and the scaffold in blue.
This is peptide IGP4 that shows interaction with ssr1 protein from Candida glabrata