Team:Goettingen/project overview/project drylab results

From 2014.igem.org

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<h1><center><b>Dry lab</b></center></h1>
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<h1>Dry lab</h1>
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<br /><h2><font color = "green"><center><b>Results summary:</b></font> <br /><br />
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<br /><h2>Results summary<br /><br />
<p>We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.</p><br />
<p>We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.</p><br />
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<font color = "blue">This is peptide IGP4 that shows interaction with ssr1 protein from <i> Candida glabrata</i><br /></center></font></h2>
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<p>This is peptide IGP4 that shows interaction with ssr1 protein from <i> Candida glabrata</i><br />
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<center><iframe width="200"  src="//www.youtube.com/embed/_SblUolgVQI" frameborder="0" allowfullscreen></iframe></center>
<center><iframe width="200"  src="//www.youtube.com/embed/_SblUolgVQI" frameborder="0" allowfullscreen></iframe></center>

Revision as of 11:16, 2 October 2014

10/15



Dry lab


Results summary

We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.


Peptide PNG* PDB Peptide location QMEAN score Overall DOPE score Energy profile
Prey 3 Download K17-E42 0.512 -7053.966797 Download
Prey 4.1 Download K17-E44 0.468 -7246.956055 Download
Prey 5 Download K17-E44 0.495 -7501.071777 Download
Prey 13 Download K17-E42 0.535 -7729.056152 Download
Prey 15 Download K17-E42 0.447 -7671.660156 Download

*The peptide is shown in red and the scaffold in blue.



This is peptide IGP4 that shows interaction with ssr1 protein from Candida glabrata




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