Team:Goettingen/project overview/project drylab results

From 2014.igem.org

(Difference between revisions)
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<td><a href="https://static.igem.org/mediawiki/2014/6/62/Goettingen-Prey3.png" target="1"><img src="https://static.igem.org/mediawiki/2014/6/62/Goettingen-Prey3.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/6/62/Goettingen-Prey3.png" target="1"><img src="https://static.igem.org/mediawiki/2014/6/62/Goettingen-Prey3.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/1/1e/Goettingen-Prey3-input.txt" target="1">Download</a></td>
<td><a href="https://static.igem.org/mediawiki/2014/1/1e/Goettingen-Prey3-input.txt" target="1">Download</a></td>
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<td style="font-size:80%;">interacting with Sim1 protein of <i>Candida albicans</i></td>
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<td style="font-size:80%;">Interacting with Sim1 protein of <i>Candida albicans</i></td>
<td>K17-E42</td>
<td>K17-E42</td>
<td>-6637.57959</td>
<td>-6637.57959</td>
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<td><a href="https://static.igem.org/mediawiki/2014/6/6e/Goettingen-Prey4-1.png" target="1"><img src="https://static.igem.org/mediawiki/2014/6/6e/Goettingen-Prey4-1.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/6/6e/Goettingen-Prey4-1.png" target="1"><img src="https://static.igem.org/mediawiki/2014/6/6e/Goettingen-Prey4-1.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/1/1b/Goettingen-Prey4-1.txt" target="1">Download</a></td>
<td><a href="https://static.igem.org/mediawiki/2014/1/1b/Goettingen-Prey4-1.txt" target="1">Download</a></td>
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<td style="font-size:80%;"> interacting with Ssr1(CAGL0H06413g) protein of <i>Candida glabrata</i></td>
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<td style="font-size:80%;">Interacting with Ssr1(CAGL0H06413g) protein of <i>Candida glabrata</i></td>
<td>K17-E44</td>
<td>K17-E44</td>
<td>-6253.714355</td>
<td>-6253.714355</td>
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<td><a href="https://static.igem.org/mediawiki/2014/4/4e/Goettingen-Prey5.png" target="1"><img src="https://static.igem.org/mediawiki/2014/4/4e/Goettingen-Prey5.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/4/4e/Goettingen-Prey5.png" target="1"><img src="https://static.igem.org/mediawiki/2014/4/4e/Goettingen-Prey5.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/8/86/Goettingen-Prey5.txt" target="1">Download</a></td>
<td><a href="https://static.igem.org/mediawiki/2014/8/86/Goettingen-Prey5.txt" target="1">Download</a></td>
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<td style="font-size:80%;">interacting with Pir4 (CAGL0I06160g) protein of <i>Candida glabrata</i></td>
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<td style="font-size:80%;">Interacting with Pir4 (CAGL0I06160g) protein of <i>Candida glabrata</i></td>
<td>K17-E44</td>
<td>K17-E44</td>
<td>-6363.106934</td>
<td>-6363.106934</td>
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<td><a href="https://static.igem.org/mediawiki/2014/1/1c/Prey13.png" target="1"><img src="https://static.igem.org/mediawiki/2014/1/1c/Prey13.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/1/1c/Prey13.png" target="1"><img src="https://static.igem.org/mediawiki/2014/1/1c/Prey13.png" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/8/8e/Goettingen-Prey13-input.txt" target="1">Download</a></td>
<td><a href="https://static.igem.org/mediawiki/2014/8/8e/Goettingen-Prey13-input.txt" target="1">Download</a></td>
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<td style="font-size:80%;">interacting with Sun1 protein of <i>Aspergillus fumigatus</i></td>
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<td style="font-size:80%;">Interacting with Sun1 protein of <i>Aspergillus fumigatus</i></td>
<td>K17-E42</td>
<td>K17-E42</td>
<td>-6283.989258</td>
<td>-6283.989258</td>
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<td><a href="https://static.igem.org/mediawiki/2014/4/41/Prey15.png"><img src="https://static.igem.org/mediawiki/2014/4/41/Prey15.png" target="1" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/4/41/Prey15.png"><img src="https://static.igem.org/mediawiki/2014/4/41/Prey15.png" target="1" width=100></a></td>
<td><a href="https://static.igem.org/mediawiki/2014/7/77/Goettingen-Prey15-input.txt" target="1">Download</a></td>
<td><a href="https://static.igem.org/mediawiki/2014/7/77/Goettingen-Prey15-input.txt" target="1">Download</a></td>
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<td style="font-size:80%;">interacting with Als3 protein of <i>Candida albicans</i></td>
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<td style="font-size:80%;">Interacting with Als3 protein of <i>Candida albicans</i></td>
<td>K17-E42</td>
<td>K17-E42</td>
<td>-6786.918457</td>
<td>-6786.918457</td>

Revision as of 10:46, 24 September 2014

10/15



Dry lab


Results summary:

This is peptide IGP4 that shows interaction with ssr1 protein from Candida glabrata





We obtained working structural models for our peptides inside their scaffolds. The following table is a summary of them. Please note that these models are not definitive, since they were obtained by homology modeling and loop refinement. Their main purpose is to give us an idea if the calculated energy profile matches our assumption that the peptide is being exposed to the exterior of the scaffold.


Peptide PNG* PDB Description Peptide location Overall DOPE score Energy profile
Prey 3 Download Interacting with Sim1 protein of Candida albicans K17-E42 -6637.57959 Download
Prey 4.1 Download Interacting with Ssr1(CAGL0H06413g) protein of Candida glabrata K17-E44 -6253.714355 Download
Prey 5 Download Interacting with Pir4 (CAGL0I06160g) protein of Candida glabrata K17-E44 -6363.106934 Download
Prey 13 Download Interacting with Sun1 protein of Aspergillus fumigatus K17-E42 -6283.989258 Download
Prey 15 Download Interacting with Als3 protein of Candida albicans K17-E42 -6786.918457 Download
*The peptide is shown in red and the scaffold in blue.

10/15