"
Team:Heidelberg/Modeling
From 2014.igem.org
(Difference between revisions)
m |
|||
| (8 intermediate revisions not shown) | |||
| Line 14: | Line 14: | ||
title=MODELING | title=MODELING | ||
| | | | ||
| - | subtitle= | + | subtitle=Quantitative insights |
| | | | ||
white=true | white=true | ||
| Line 48: | Line 48: | ||
<a href="/Team:Heidelberg/Modeling/Linker_Modeling" class="box" style="display:block; width:100%;"> | <a href="/Team:Heidelberg/Modeling/Linker_Modeling" class="box" style="display:block; width:100%;"> | ||
<h2><span>LINKER MODELING</span></h2> | <h2><span>LINKER MODELING</span></h2> | ||
| - | + | The design of linkers, which are essential for our intein-based circularization and assembly methods, is a complicated task. Here we employ structural modeling and statistical analyses to guide our linker experiments and their design. | |
<div class="clearfix"></div> | <div class="clearfix"></div> | ||
</a> | </a> | ||
| Line 55: | Line 55: | ||
<div style="width:100%;padding:0 15px 0 15px;"> | <div style="width:100%;padding:0 15px 0 15px;"> | ||
<a href="/Team:Heidelberg/Modeling/Enzyme_Modeling" class="box" style="display:block; width:100%;"> | <a href="/Team:Heidelberg/Modeling/Enzyme_Modeling" class="box" style="display:block; width:100%;"> | ||
| - | <h2><span> | + | <h2><span>ENZYME KINETICS MODELING</span></h2> |
| - | + | Based on over 1000 degradation curves of our circularized lysozyme variants, we tried to interpret the effect of linkers on protein thermostability. This was achieved by use of quantitative dynamical modeling. | |
<div class="clearfix"></div> | <div class="clearfix"></div> | ||
</a> | </a> | ||
| Line 64: | Line 64: | ||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
| - | |||
</div> | </div> | ||
Latest revision as of 03:04, 18 October 2014
MODELING
– Quantitative insights
