Team:Waterloo

From 2014.igem.org

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<h1>Staphylocide</h1>
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<h3 style="text-align: center">Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
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<h3 style="text-align: center">Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
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Latest revision as of 02:33, 18 October 2014

Waterloo iGem 2014 Team

Staphylocide

Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation

Problem

MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...

Solution

...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.

 

Project Cornerstones

Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.