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Team:Waterloo
From 2014.igem.org
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<h1>Staphylocide</h1> | <h1>Staphylocide</h1> | ||
| - | <h3>Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3> | + | <h3 style="text-align: center">Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3> |
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<div class="content"> | <div class="content"> | ||
<div class="tabcontents"> | <div class="tabcontents"> | ||
<div class="anchor" id="view0" style="padding-top:0px;"> | <div class="anchor" id="view0" style="padding-top:0px;"> | ||
| - | <div style="padding-bottom: | + | <div style="padding-bottom:50px; min-height: 150px;"> |
| - | <div class="half-column | + | <div class="half-column floatLeft"> |
| - | <h2 | + | <h2 style="text-transform:uppercase;">Problem</h2> |
| - | <img class=" | + | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" /> |
| - | . | + | <p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p> |
</div> | </div> | ||
| - | <div | + | <div class="half-column floatRight"> |
| - | <h2 | + | <h2 style="text-transform:uppercase;">Solution</h2> |
| - | <img class=" | + | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" /> |
| - | + | <p>...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing <em>in vivo</em> and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.</p> | |
</div> | </div> | ||
</div> | </div> | ||
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<h2 style="text-align: center">Project Cornerstones</h2> | <h2 style="text-align: center">Project Cornerstones</h2> | ||
| + | <p style="text-align: center">Explore the three cornerstones of this year's project: <a href="https://2014.igem.org/Team:Waterloo/Deliver">delivering</a> the silencing <em>in vivo</em> using conjugation, <a href="https://2014.igem.org/Team:Waterloo/Silence">silencing</a> <em>mecA</em> expression using CRISPRi and sRNA and <a href="https://2014.igem.org/Team:Waterloo/Translate">translating</a> from the lab to the patients.</p> | ||
<div style="padding:5px; text-align:center; width:100%;"> | <div style="padding:5px; text-align:center; width:100%;"> | ||
<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a> | <a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a> | ||
Revision as of 22:02, 17 October 2014
Staphylocide
Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation
Problem
MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...
Solution
...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.
Project Cornerstones
Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.
