Team:WPI-Worcester

From 2014.igem.org

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<li><a href="#"><center><img src="https://static.igem.org/mediawiki/2014/d/d4/WPI_Safety_Link.png"/></center><p>Practices</p></a>  
<li><a href="#"><center><img src="https://static.igem.org/mediawiki/2014/d/d4/WPI_Safety_Link.png"/></center><p>Practices</p></a>  
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                <li><a href="https://2014.igem.org/Team:WPI-Worcester/Outreach">Outreach</a></li>
             <li><a href="https://2014.igem.org/Team:WPI-Worcester/Survey">Survey</a></li>
             <li><a href="https://2014.igem.org/Team:WPI-Worcester/Survey">Survey</a></li>
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            <li><a href="https://2014.igem.org/Team:WPI-Worcester/Outreach">Outreach</a></li>
 
  <li><a href="https://2014.igem.org/Team:WPI-Worcester/Collaborations">Collaborations</a></li>
  <li><a href="https://2014.igem.org/Team:WPI-Worcester/Collaborations">Collaborations</a></li>
<li><a href="https://2014.igem.org/Team:WPI-Worcester/Interlab">Interlab Study</a></li>
<li><a href="https://2014.igem.org/Team:WPI-Worcester/Interlab">Interlab Study</a></li>

Revision as of 18:28, 17 October 2014

Team:WPI-Worcester - 2014.igem.org

 

Team:WPI-Worcester

From 2014.igem.org


Ag-goat-ination:

Combating Antibiotic Resistance through Diagnostic Agglutination Assays

Just this year, in a vote held for the Longitude Prize, antibiotic resistance was voted the most pressing issue of our time. One of the biggest causes of antibiotic resistance lies in the farming industry; more than 3 times the amount of antibiotics given to humans are administered to livestock. Over-prescription of antibiotics promotes resistance in both livestock pathogens and natural flora, which can be transmitted to humans through meat and other products.

A cheap, quick, and reliable mechanism for detecting and identifying infection is one solution to this problem. We developed an E.coli based cell surface antigen expression system that can be utilized as a diagnostic tool for nearly any viral, bacterial, or fungal infection. The recombinant E.coli are utilized in a direct agglutination test using the host organism’s serum. Our team successfully demonstrated the feasibility of this diagnostic tool using a GFP antibody and antigen pair.