Team:ULB-Brussels/Safety

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Revision as of 11:45, 1 August 2014

$~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\MyColi}{{\small Mighty\hspace{0.12cm}Coli}} \newcommand{\Stabi}{\small Stabi}$ $\newcommand{\EColi}{\small E.coli} \newcommand{\SCere}{\small S.cerevisae}\\[0cm] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\PI}{\small PI}$ $\newcommand{\Igo}{\Large\mathcal{I}} \newcommand{\Tgo}{\Large\mathcal{T}} \newcommand{\Ogo}{\Large\mathcal{O}} ~$ Example of a hierarchical menu in CSS

- Université Libre de Bruxelles -

Safety

To avoid an eventual contamination and apply the emergency mesures in the lab,

deep attention is taken to use safely our lab equipement and our EColi bacteria.

Because our system could be used to enhance the production of a dangerous protein,

gloves, glasses and coat are part of our usual equipment,

especially during electrophoresis.

The containment of the bacteria should not be a primary issue:

Indeed, our project has a build-in biocontainment component. The antitoxin production is under

the control of an arabinose-dependant promoter. If the bacteria escape from the bioreactor, they will no longer

be provided with arabinose, thus they will stop producing the antitoxin and they will quickly die.

-

@@ Line 22: / Line 22: @@
 The containment of the bacteria should not be a primary issue: </p>
-it is the reason why our project doesn't currently include a biocontainment component. </p>
+Indeed, our project has a build-in biocontainment component. The antitoxin production is under </p>
-However, we could easily manage to include an inhibitor of the transcription of the antitoxin </p>
+the control of an arabinose-dependant promoter. If the bacteria escape from the bioreactor, they will no longer </p>
-under the control of an environmental signal. </p>
+be provided with arabinose, thus they will stop producing the antitoxin and they will quickly die. </p>
 -</section>