Team:ULB-Brussels/Safety
From 2014.igem.org
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<script type="text/x-mathjax-config"> MathJax.Hub.Config({ tex2jax: {inlineMath: [['$','$'], ['\\(','\\)']]} });</script> | <script type="text/x-mathjax-config"> MathJax.Hub.Config({ tex2jax: {inlineMath: [['$','$'], ['\\(','\\)']]} });</script> | ||
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- | <!-- | + | <!-- --> |
- | \newcommand{\Tgo}{\Large\mathcal{T}\normalsize} | + | \newcommand{\Tgo}{\Large\mathcal{T}\normalsize} |
- | \newcommand{\MyColi}{<i>Mighty Coli </i>} | + | \newcommand{\MyColi}{<i>Mighty Coli </i>} |
\newcommand{\CC}{\mathbb{C}} | \newcommand{\CC}{\mathbb{C}} | ||
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<section style="text-align: justify; margin: 100px"> | <section style="text-align: justify; margin: 100px"> | ||
<p><!--$\Large\mathcal{T}\normalsize$--> | <p><!--$\Large\mathcal{T}\normalsize$--> | ||
- | The main concerns raised by <i>Mighty Coli</i> depend more of the protein that we chose to produce than of <i>Mighty Coli</i> in itself. However, <i>Mighty Coli</i> could compel an escaped recombinant bacterium to produce an industrial protein in the environment, when a bacterium without the $\MyColi$ system would quickly degenerate to stop producing the protein of industrial interest. The risk seems thin, since such an overproducing bacterium would suffer from a clear competitive disadvantage in a wild environment, but it is not excluded that the plasmid containing the <i>Mighty Coli</i> system maintains itself anyway through Horizontal Gene transfer (HGT), at the expend of the wild bacteria it infects, benefiting of the proprieties of the TA system.</p> | + | $\CC$ $\Tgo$The main concerns raised by <i>Mighty Coli</i> depend more of the protein that we chose to produce than of <i>Mighty Coli</i> in itself. However, <i>Mighty Coli</i> could compel an escaped recombinant bacterium to produce an industrial protein in the environment, when a bacterium without the $\MyColi$ system would quickly degenerate to stop producing the protein of industrial interest. The risk seems thin, since such an overproducing bacterium would suffer from a clear competitive disadvantage in a wild environment, but it is not excluded that the plasmid containing the <i>Mighty Coli</i> system maintains itself anyway through Horizontal Gene transfer (HGT), at the expend of the wild bacteria it infects, benefiting of the proprieties of the TA system.</p> |
<section style="text-align: justify; margin: 20px"></section> | <section style="text-align: justify; margin: 20px"></section> |
Revision as of 07:25, 11 September 2014
$~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\MyColi}{{\small Mighty\hspace{0.12cm}Coli}} \newcommand{\Stabi}{\small Stabi}$ $\newcommand{\EColi}{\small E.coli} \newcommand{\SCere}{\small S.cerevisae}\\[0cm] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\PI}{\small PI}$ $\newcommand{\Igo}{\Large\mathcal{I}} \newcommand{\Tgo}{\Large\mathcal{T}} \newcommand{\Ogo}{\Large\mathcal{O}} ~$
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