Team:UFAM Brazil/Modeling

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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="http://2014.igem.org/wiki/index.php?title=Team:UFAM_Brazil/Modeling&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="http://2014.igem.org/Team:UFAM_Brazil"style="color:#000000">Home </a> </td>
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<a href="http://igem.org/Team.cgi?year=2014&team_name=UFAM_Brazil"style="color:#000000"> Official Team Profile </a></td>
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<a href="http://2014.igem.org/Team:UFAM_Brazil/Modeling"style="color:#000000"> Modeling</a></td>
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The Hg²+ ions uptake and entrance from the cell exterior to the interior system and its subsequent reduction to Hg<sup>0</sup> species is a complex process that has several steps for its realization. This procedure aims to transform the mercury ion in a volatile element (Hg<sup>0</sup>), able to passively diffuse through the membranes to the cell exterior.
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According to Figure 1, the uptake and reduction system operates basically with merP, merT, merC, merF and merA proteins, being the first a periplasmic protein that binds to mercury ion for carrying to one of its transporters (merT, merC or merF), which are located in the inner membrane, and release Hg²+ inside the cells. Then, Hg²+ undergoes the merA enzyme action, which can reduce Hg²+ to Hg<sup>0</sup>, thereby enables its passive exist by membrane.
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<p>If you choose to create a model during your project, please write about it here. Modeling is not an essential part of iGEM, but we encourage any and all teams to model some aspect of their project. See previous "Best Model" awards for more information.</p>
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Revision as of 18:20, 26 September 2014

The Hg²+ ions uptake and entrance from the cell exterior to the interior system and its subsequent reduction to Hg0 species is a complex process that has several steps for its realization. This procedure aims to transform the mercury ion in a volatile element (Hg0), able to passively diffuse through the membranes to the cell exterior.

According to Figure 1, the uptake and reduction system operates basically with merP, merT, merC, merF and merA proteins, being the first a periplasmic protein that binds to mercury ion for carrying to one of its transporters (merT, merC or merF), which are located in the inner membrane, and release Hg²+ inside the cells. Then, Hg²+ undergoes the merA enzyme action, which can reduce Hg²+ to Hg0, thereby enables its passive exist by membrane.