Team:Paris Bettencourt/Project

From 2014.igem.org

Revision as of 15:57, 15 October 2014 by Roussetfrancois (Talk | contribs)

SMELL THE ROSES

Here we present the design of an odor palette. It is composed of BioBricks containing coding sequences for different enzymes known to catalyze reactions that yield volatile compounds with characteristic smells. We included smells with different tonalities in order to explore the resulting aromas from combinations of smelly units.

SOMETHING FISHY

Trimethylaminuria (TMAU) is a rare genetic disease causing a strong fish odor. Our project aims at engineering skin bacteria to degrade trimethylamine, the odor causing molecule, by the enzyme TMM (trimethylamine monooxygenase).

GOODY TWO SHOES

Isovaleric acid is a compound produced by B. subtilis through leucine degradation pathway, which is hypothesized to be responsible for the foot odor (cheese smell.) Our project aims at validating this hypothesis with the aid of both invitro and insitu experimentation's.

DON'T SWEAT IT

Bacteria processing sweat is the major responsible of body odor. Our project aims to study the bacteria involved in the creation of malodorous compounds and try to find natural variant that are odorless. The final goal is to create a probiotic cosmetic.

TEEN SPIRIT

2-nonenal is a compound with very specific strong odor perceived as iris, fat, and cucumber, which rate increases with age. Our goal is to study relationship between human skin bacteria and 2-nonenal.

ART

2-nonenal is a compound, with very specific strong odor perceived as iris, fat, and cucumber, which rate increases with age. Our goal is to study relationship between human skin bacteria and 2-nonenal.

BIOINFORMATICS

Bioinformatics tools are used to analyze genes related to body odor in order to better understand gene abundance at various body sites, function and phylogeny.

This year, iGEM Paris Bettencourt is hoping to find a cure for a common problem: body odor. In order to combat this omnipresent problem, we are using synthetic biology techniques in a variety of different ways, specifically for the regular body odor smell, a genetic disease known as fish odor syndrome, foot odor, and age-related body odor.

Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
+33 1 44 41 25 22/25
paris-bettencourt-igem@googlegroups.com
Copyright (c) 2014 igem.org. All rights reserved.