Team:Oxford/biopolymer containment
From 2014.igem.org
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<h1blue2>1. Maximise rate.</h1blue2> | <h1blue2>1. Maximise rate.</h1blue2> | ||
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- | A primary function of the beads is to maximise reaction rate per bead volume; halving the radius of a sphere doubles its surface area:volume ratio. Many, small, bacteria-embedded agarose beads (to a technical limit) are therefore optimal, as the average bacterium is closer to the surface of each bead and being ‘used’ | + | A primary function of the beads is to maximise reaction rate per bead volume; halving the radius of a sphere doubles its surface area:volume ratio. Many, small, bacteria-embedded agarose beads (to a technical limit) are therefore optimal, as the average bacterium is closer to the surface of each bead and being ‘used’ efficiently. Assuming brownian motion, substrate molecules are more likely to collide with and be broken down by ‘outer’ bacteria. Product molecules, additionally, have a shorter path length to the surface and are likely to diffuse out faster: |
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<img src="https://static.igem.org/mediawiki/2014/a/aa/Oxford_polymer1.png" style="float:left;position:relative; width:70%;margin-left:15%;margin-right:15%;margin-bottom:2%;" /> | <img src="https://static.igem.org/mediawiki/2014/a/aa/Oxford_polymer1.png" style="float:left;position:relative; width:70%;margin-left:15%;margin-right:15%;margin-bottom:2%;" /> |
Revision as of 18:03, 13 October 2014