iGEM Quiz Marburg

Human Practice is an important part of the iGEM competition as we want to expand the knowledge about Synthetic Biology. During the discussion with people visiting our booth at "Drei-Tage-Marburg" and "Hessentag" we discovered a huge lack of knowledge in this field. Especially gene technology is not part of the common knowledge but we were able to answer a lot of questions. We strongly believe in the importance of the knowledge about synthetic biology since this new field will have impact on all our lives in the future and now is the time to close those knowledge gaps. The audience we were able to talk to during those events was limited, so we decided to go online and create an application available on all common platforms. Thereby we are able to reach a much wider audience of different age to fill those gaps in common knowledge.

For presenting the information in a playful way we chose a quiz style app instead of just a non-interactive learning platform. This quiz enables us not only to precisely check for knowledge in specific fields. In order to get an overview of users’ level of knowledge we integrated an interaction between our app and our server by collecting the users answers anonymously. With the help of the collected data we are not only able to adapt our quiz depending on the given answers but also to perform statistical analyses. Our system is completely extendible by submitting new questions at any time.

In addition to the regular quiz we integrated the “Game of Genethics”. This part of the app is not about wrong or right answers but how the users are reacting to controversial decisions of real biotechnological applications. After biotechnology is working by altering genes in organisms, bioethics is an important topic to consider discussing ethical borders.

By integration of an online high score system for every participant we aimed to draw more attention towards the game and to add a competitive aspect. Depending on the difficulty of the questions and the time the user needs to answer the questions he earns more or less points. Those points will be combined to form one total high score. The best players will be able to win a special price in the end.

Screenshots of the home screen and some example questions from the "greenhorn" category.
Screetshots from the "Game of Genethics"

Results

The following results are based on data collected during a period of two months. We analysed over 13.000 responses given by users from around the globe. We are able to correlate the datasets with gender, age, relation to the field of synthetic biology and participation in the iGEM competition, assuming that every user entered honest information.

Besides expected outcomes like correlation between contact with synthetic biology and right answers in the first round, we found some surprising results.

The most encouraging unexpected result was the strong increase in the learning curve of users without iGEM participation compared to participants.

Figure: Right answers after two attempts

In the second attempt the users without an iGEM background were able to memorize most of the questions, increasing their rate of right answers from 65.8% to fantastic 90.7%, while the participants’ learning curve just increase by 2.6% from 70.2% to 72.8%.

Altogether we can confirm a strong increase of right answers in the second approach. Thereby we are able to verify the success of our app towards our goal to teach synthetic biology to a wide audience.

The following questions are the top five right answered questions with rates of positive answers over 90%...

1. What are the components of proteins?
2. What is Escherichia coli?
3. What is a Dalton?
4. What is green Biotechnology?
5. What does PCR stand for?

...do you also know the answer?