Team:ITB Indonesia/SelfMod

From 2014.igem.org

(Difference between revisions)
Line 195: Line 195:
<li>WETLAB
<li>WETLAB
<ul>
<ul>
-
<li><a href="">PARTS</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/protocol">PROTOCOL</a></li>
-
<li><a href="">ATTRIBUTIONS</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Parts">PARTS</a></li>
 +
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Attributions">ATTRIBUTIONS</a></li>
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Safety">SAFETY</a></li>
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Safety">SAFETY</a></li>
-
<li><a href="">DATA</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Data">DATA</a></li>
-
<li><a href="">PROTEIN MODEL</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/ProteinModel">PROTEIN MODEL</a></li>
-
<li><a href="">ACHIEVEMENT</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Achievement">ACHIEVEMENT</a></li>
</ul>
</ul>
</li>
</li>
<li>NOTEBOOK
<li>NOTEBOOK
<ul>
<ul>
-
<li><a href="">MODELING</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/nb-modeling">MODELING</a></li>
-
<li><a href="https://igem.org/Team.cgi?id=1387">WETLAB</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/nb-wetlab">WETLAB</a></li>
</ul>
</ul>
</li>
</li>
Line 217: Line 218:
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/OnMedia">MEDIA</a></li>
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/OnMedia">MEDIA</a></li>
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Biosafety">BIOSAFETY SEMINAR</a></li>
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Biosafety">BIOSAFETY SEMINAR</a></li>
-
<li><a href="">INDONESIA TEAMS MEET UP</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/MeetUp">INDONESIA TEAMS MEET UP</a></li>
-
<li><a href="">FUN WITH KIDS</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Kids">FUN WITH KIDS</a></li>
-
<li><a href="">SHARING SYNBIO IN UPI</a></li>
+
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/UPI">SHARING SYNBIO IN UPI</a></li>
</ul>
</ul>
</li>
</li>

Revision as of 00:51, 15 October 2014


Self Regulatory Module

Self-regulatory module is designed to repair the inefficiency of system due to formation of inclusion body. Inclusion body is formed from aggregation of misfolded protein caused by overexpression of LC Cutinase protein (degradation module). Besides being inefficient to the system, inclusion body may also kill the organism because it gives a cytoplasmic stress to cell.

When inclusion body occurs, inclusion body inducible promoter (PibpAB) will active and the expression of TetR repressor will take place. This TetR repressor then corresponds to TetO in degradation module and inhibits the expression of LC Cutinase protein. This inhibition effect will eventually decreasing the inclusion body present in the cell and improving the system efficiency.