Team:Goettingen/notebook drylab

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Revision as of 19:52, 11 September 2014

Homology modelling

We're trying to model the tridimensional structure of our peptide-containing scaffolds (domain B1 from protein G from Streptococcus aureus). We're using homology modelling with the Modeller library to accomplish that, since the peptide is about 25-25 amino acid residues long and it can be modelled as a loop inside the B1 domain scaffold, for which there are already a number of 3D structures available at the Protein Data Bank.