Team:Dundee

From 2014.igem.org

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         <h4 class="modal-title" id="myModalLabel">Welcome to Dundee's 2014 Wiki</h4>
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         <h4 class="modal-title" id="myModalLabel">Welcome to Dundee's 2014 Wiki (<b>Site Information</b>)</h4>
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   Cystic Fibrosis is a genetic disease that results in the accumulation of thick mucus in the epithelial linings of the entire body, particularly the respiratory tract. Over the course of a patient’s life the mucus-lined lung epithelium becomes repeatedly infected with pathogenic bacteria that stimulate an immune response, leading to inflammation, tissue damage, and ultimately, respiratory failure.   
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   Cystic Fibrosis is a genetic disease that results in the accumulation of thick mucus in the epithelial linings of the entire body, particularly the respiratory tract. Over the course of a patient’s life, the mucus-lined lung epithelium becomes repeatedly infected with pathogenic bacteria that stimulate an immune response; leading to inflammation, tissue damage, and ultimately, respiratory failure.   
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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is <i>Staphylococcus aureus</i>, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, <i>Pseudomonas aeruginosa</i> and <i>Burkholderia cepacia</i>, are very difficult to eradicate and are associated with chronic decline in lung function. <i>Burkholderia</i> is so infectious, that patients have to be isolated from one another, and can be denied lung transplants due to the persistance of this bacterium.  
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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is <i>Staphylococcus aureus</i>, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, <i>Pseudomonas aeruginosa</i> and <i>Burkholderia cepacia</i>, are very difficult to eradicate and are associated with chronic decline in lung function. <i>Burkholderia</i> is so infectious that patients have to be isolated from one another, and can be denied lung transplants due to the persistence of this bacterium.  
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Read this again by clicking on the board!       
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Read this again by clicking on <b>Site Information</b> in the navigation bar!       
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     <h3>School</h3>  
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     <h3>Bulletin Board (Policy & Practice)</h3>  
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    Come look at the poster explaining how we involved the local and national Cystic Fibrosis community in our project, how we listened to people on the front line of the disease and how they affected our project.
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     <h3>School</h3>  
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     <h3>School (Project)</h3>  
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      Come in and learn about all the parts that make The Lung Ranger. The lab work that we carried out over the   
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         summer is explained here in detail, along with the modelling and implementation.  
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<h3>Library (Log Book)</h3>  
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         Read about the experience the team has had over the summer. A week by week description of our work, how we carried out that work and some photos of our time together.
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  <h3>Saloon</h3>  
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  <h3>Saloon (iGEM community)</h3>  
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Come on in, take a seat and learn how we have interacted with the larger iGEM community. Who the team are, who helped them and how we helped others.
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EASTBIO - the BBSRC East of Scotland Bioscience Doctoral Training Partnership - is a partnership between the Universities of Aberdeen, Dundee, Edinburgh and St Andrews; the Scottish Universities Life Sciences Alliance (SULSA); and the Scottish Universities Physics Alliance (SUPA).
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EASTBIO - the BBSRC East of Scotland Bioscience Doctoral Training Partnership - is a partnership between the Universities of Aberdeen, Dundee, Edinburgh and St Andrews; the Scottish Universities Life Sciences Alliance; and the Scottish Universities Physics Alliance. The DTP scheme will provide students with excellent cross-disciplinary research training in line with the current BBSRC strategy for research support and training.
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Latest revision as of 22:47, 17 October 2014

Dundee 2014