Safety/White List

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Questions or feedback?
Email safety AT igem DOT org!

PAGE UNDER CONSTRUCTION -- NOT READY FOR USE

This White List is a draft. It is not the final version!

Questions? Contact

  1. Obtain Claudia's feedback on white list
  2. Consult VFDB / protein taxonomies
  3. Format nicely and post
  4. Write FAQ
  5. Remove this note.


Remember!

You must Check-In for ANY organism or part that is NOT on the White List. The right-hand column of the table below is only examples of organisms/parts that require a Check-In. If your part/organism is not in the table below, it still requires a Check-In.

Questions? Contact



White List (no Check-In required) Check-In Required
Whole Organisms
  • Risk Group 1
  • Human and primate cell lines that have been tested and certified free of known pathogens (consult your vendor)
  • Cell lines of non-primate multicellular organisms
  • C. elegans, Physcomitrella patens, Drosophila spp.
  • Risk Groups 2, 3, 4
  • All primary isolated cells
  • Human and primate cell lines that may contain known pathogens
  • Other multicellular organisms
  • ...and anything not explicitly listed
Parts
  • Any part from a Risk Group 1 organism, regardless of its function
  • All Registry parts, except those flagged by Archetype or Safety Committee
  • Non-protein-coding parts in the following categories:
    • Promoters, RBSes, Terminators
    • Binding sites for transcriptional regulators, endonucleases, and other proteins that bind to DNA
    • CRISPR guide RNAs, microRNAs / interfering RNAs, aptamers
  • Protein-coding genes from animals, plants, or Risk Group 2 microorganisms, in the following categories:
    • Category 1
    • Category 2
  • Any part from a Risk Group 3 or 4 organism, regardless of its function
  • Registry parts with red flags on
  • Non-protein-coding genes that do not fall in any of the white-listed categories
  • Protein-coding genes from animals, plants, or Risk Group 2 microorganisms, that do not fall in any of the white-listed categories


Banned Organisms/Parts

Some of the most dangerous organisms and parts are not allowed in iGEM, even with a Check-In:

  • Whole organisms from Risk Group 3
  • Whole organisms from Risk Group 4
  • Parts from Risk Group 4 organisms

Notes

What if I'm not sure whether my organism/part requires a Check-In?

Ask us! Contact safety AT igem DOT org. Alternatively, because the Check-In form is short, you could choose to send a Check-In even if you are unsure.

We are going to handle an organism in lab, but we will only extract some DNA from it using PCR -- we won't use it as our chassis. Do we still have to send a Check-In?

Our project is to detect a dangerous organism. In order to test our project, of course we need to handle the dangerous organism (or parts of it), but it will not be part of what we build. Do we still have to send a Check-In?

Yes. The Check-In requirement applies to all organisms and all parts that you will handle in the lab, even if they will not be part of your final project.

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