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Team:Groningen/Template/MODULE/project/MBD/diffusionrates
From 2014.igem.org
6 bandage designs
Studying the diffusion rates of Nisin, Aiia and DspB is important to estimate the time taken to reach the threshold concentrations. The threshold concentration is the minimum concentration of the proteins that is required to breakdown biofilm, kill Staphylococcus aureus and quorum quench Pseudomonas aeruginosa population. The diffusion constants for these three proteins were not available directly. They were calculated using number formulas. Diffusion rate inside the polyacrylamide gel is different from the diffusion in a solvent.
Figure-movie 1
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The bacteria are uniformly distributed all over the hydrogel in the bandage.
Figure-movie 2
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Instead of having uniform bacterial distribution, we have single layer of bacteria beneath the top membrane of the bandage.
Figure-movie 3
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Single layer of bacteria are placed in the bottom of the bandage.
Figure-movie 4
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Single layer of bacteria is placed in the middle of the gel.
Figure-movie 5
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Bacteria are localized to a single lattice in the top of the bandage.
Figure-movie 6
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Bacteria are localized to two separate lattices in the middle of the bandage.
