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Team:Groningen:Project:Detection/staphaureus
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Detection of Pseudomonas aeruginosa
Quorum sensing pathway in Pseudomonas aeruginosa
The Quorum sensing system of pseudomonas aeruginosa of multiple hierarchically ordered complex. In one layer of this complex system two proteins are synthesized, LasR and LasI. The LasI produces AHLs which can bind with the LasR. The LasR-AHL couple induces expression of virulence factors LasA protease, alkaline protease and exotoxin A. Moreover, the couple acts as autoinducer on the expression of LasI by influencing the promoter pLasI, increasing the synthesis of AHLs.(Papaioannou, Utari, & Quax, 2013). AHLs can move from cell to cell and thus influencing the QS of other cells in the surrounding.
Figure 1:
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Figure 1:
Vivamus a augue diam. Nam hendrerit nisi ut tellus hendrerit, ac volutpat massa tristique.
