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Team:Groningen/Template/MODULE/project/MBD/results
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Conclusion
| Design | Tnisin | TAiiA | TDspB | Rating |
|---|---|---|---|---|
| 1 | 3 h | something | something | something |
| 2 | ? | After being applied to the wound. Amount of time for reaching the inhibitory concentrations of nisin, DspB and AiiA to pass the bottom membrane and into the wound. | ||
| 3 | tbd | In what quantity does S. aureus need to be detected? | ||
| 4 | tbd | In what quantity does P. aeruginosa need to be detected? | ||
| 5 | 2-16 ng/µL | This concentration can be used for both MRSA and VRE. Source: Nisin, alone and combined with peptidoglycan-modulating antibiotics: activity ……. Brumfitt, Salton, Hamilton-Miller. | ||
| 6 | tbd | How much is needed to inhibit growth of PA/SA? |
Final outcome of the modeling is that design 1 is the best, with all the cells evenly distributed throughout the hydrogel.
Figure 1:
The best design for our purposes.
