MS2 Box

The MS2 box acts as a binding site for the MS2 coat protein, formed downstream in the replicon, which represses translation hence preventing exponential growth of the replicon. Exploiting the MS2 box-protein binding relationship is known as MS2 tagging.

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MS2 Coat Protein

This coding sequence forms a protein which binds to the MS2 box, hairpin type structure, and represses translation of the replicon.

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