Team:NTU Taida/Circuit3

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NTU-Taida

Corneum decomposition --- Keratinaes

  • Inspiration :

    Exfoliation involves the removal of the oldest dead skin cells on the skin's outermost surface to help maintain healthy skin, softening the look of wrinkles and promoting collagen production.Keratinase is enzyme derived from Streptomyces fradiac to degrade the disulfide (-S-S-) bond of the keratin substrate, and its effect on human skin has not been previously reported.Since the second part share the ideas with the first part, the principle mechanism is the same. When E-coli is in fatty-acids-deficient surroundings, the production of keratinases is inhibited. The adequate fatty acids will resulting in the production of keratinases. CI coding region, pCI coding region, and different ribosome biding sites (RBS) are put into the circuit to ensure the shutting down of the keratinase gene after some time.
  • Testing Result :

  • Background Knowledge :

  • Reference :