"
Team:Melbourne
From 2014.igem.org
<head> <style> /* CSS Document */ /*! normalize.css v2.1.2 | MIT License | git.io/normalize */
/* ==========================================================================
HTML5 display definitions ========================================================================== */
/**
* Correct `block` display not defined in IE 8/9. */
article, aside, details, figcaption, figure, footer, header, hgroup, main, nav, section, summary {
display: block;
}
/**
* Correct `inline-block` display not defined in IE 8/9. */
audio, canvas, video {
display: inline-block;
}
/**
* Prevent modern browsers from displaying `audio` without controls. * Remove excess height in iOS 5 devices. */
audio:not([controls]) {
display: none; height: 0;
}
/**
* Address styling not present in IE 8/9. */
[hidden] {
display: none;
}
/* ==========================================================================
Base ========================================================================== */
/**
* 1. Set default font family to sans-serif. * 2. Prevent iOS text size adjust after orientation change, without disabling * user zoom. */
html {
font-family: sans-serif; /* 1 */ -ms-text-size-adjust: 100%; /* 2 */ -webkit-text-size-adjust: 100%; /* 2 */
}
/**
* Remove default margin. */
body {
margin: 0;
}
/* ==========================================================================
Links ========================================================================== */
/**
* Address `outline` inconsistency between Chrome and other browsers. */
a:focus {
outline: thin dotted;
}
/**
* Improve readability when focused and also mouse hovered in all browsers. */
a:active, a:hover {
outline: 0;
}
/* ==========================================================================
Typography ========================================================================== */
/**
* Address variable `h1` font-size and margin within `section` and `article` * contexts in Firefox 4+, Safari 5, and Chrome. */
h1 {
font-size: 2em; margin: 0.67em 0;
}
/**
* Address styling not present in IE 8/9, Safari 5, and Chrome. */
abbr[title] {
border-bottom: 1px dotted;
}
/**
* Address style set to `bolder` in Firefox 4+, Safari 5, and Chrome. */
b, strong {
font-weight: bold;
}
/**
* Address styling not present in Safari 5 and Chrome. */
dfn {
font-style: italic;
}
/**
* Address differences between Firefox and other browsers. */
hr {
-moz-box-sizing: content-box; box-sizing: content-box; height: 0;
}
/**
* Address styling not present in IE 8/9. */
mark {
background: #ff0; color: #000;
}
/**
* Correct font family set oddly in Safari 5 and Chrome. */
code, kbd, pre, samp {
font-family: monospace, serif; font-size: 1em;
}
/**
* Improve readability of pre-formatted text in all browsers. */
pre {
white-space: pre-wrap;
}
/**
* Set consistent quote types. */
q {
quotes: "\201C" "\201D" "\2018" "\2019";
}
/**
* Address inconsistent and variable font size in all browsers. */
small {
font-size: 80%;
}
/**
* Prevent `sub` and `sup` affecting `line-height` in all browsers. */
sub, sup {
font-size: 75%; line-height: 0; position: relative; vertical-align: baseline;
}
sup {
top: -0.5em;
}
sub {
bottom: -0.25em;
}
/* ==========================================================================
Embedded content ========================================================================== */
/**
* Remove border when inside `a` element in IE 8/9. */
img {
border: 0;
}
/**
* Correct overflow displayed oddly in IE 9. */
svg:not(:root) {
overflow: hidden;
}
/* ==========================================================================
Figures ========================================================================== */
/**
* Address margin not present in IE 8/9 and Safari 5. */
figure {
margin: 0;
}
/* ==========================================================================
Forms ========================================================================== */
/**
* Define consistent border, margin, and padding. */
fieldset {
border: 1px solid #c0c0c0; margin: 0 2px; padding: 0.35em 0.625em 0.75em;
}
/**
* 1. Correct `color` not being inherited in IE 8/9. * 2. Remove padding so people aren't caught out if they zero out fieldsets. */
legend {
border: 0; /* 1 */ padding: 0; /* 2 */
}
/**
* 1. Correct font family not being inherited in all browsers. * 2. Correct font size not being inherited in all browsers. * 3. Address margins set differently in Firefox 4+, Safari 5, and Chrome. */
button, input, select, textarea {
font-family: inherit; /* 1 */ font-size: 100%; /* 2 */ margin: 0; /* 3 */
}
/**
* Address Firefox 4+ setting `line-height` on `input` using `!important` in * the UA stylesheet. */
button, input {
line-height: normal;
}
/**
* Address inconsistent `text-transform` inheritance for `button` and `select`. * All other form control elements do not inherit `text-transform` values. * Correct `button` style inheritance in Chrome, Safari 5+, and IE 8+. * Correct `select` style inheritance in Firefox 4+ and Opera. */
button, select {
text-transform: none;
}
/**
* 1. Avoid the WebKit bug in Android 4.0.* where (2) destroys native `audio` * and `video` controls. * 2. Correct inability to style clickable `input` types in iOS. * 3. Improve usability and consistency of cursor style between image-type * `input` and others. */
button, html input[type="button"], /* 1 */ input[type="reset"], input[type="submit"] {
-webkit-appearance: button; /* 2 */ cursor: pointer; /* 3 */
}
/**
* Re-set default cursor for disabled elements. */
button[disabled], html input[disabled] {
cursor: default;
}
/**
* 1. Address box sizing set to `content-box` in IE 8/9. * 2. Remove excess padding in IE 8/9. */
input[type="checkbox"], input[type="radio"] {
box-sizing: border-box; /* 1 */ padding: 0; /* 2 */
}
/**
* 1. Address `appearance` set to `searchfield` in Safari 5 and Chrome. * 2. Address `box-sizing` set to `border-box` in Safari 5 and Chrome * (include `-moz` to future-proof). */
input[type="search"] {
-webkit-appearance: textfield; /* 1 */ -moz-box-sizing: content-box; -webkit-box-sizing: content-box; /* 2 */ box-sizing: content-box;
}
/**
* Remove inner padding and search cancel button in Safari 5 and Chrome * on OS X. */
input[type="search"]::-webkit-search-cancel-button, input[type="search"]::-webkit-search-decoration {
-webkit-appearance: none;
}
/**
* Remove inner padding and border in Firefox 4+. */
button::-moz-focus-inner, input::-moz-focus-inner {
border: 0; padding: 0;
}
/**
* 1. Remove default vertical scrollbar in IE 8/9. * 2. Improve readability and alignment in all browsers. */
textarea {
overflow: auto; /* 1 */ vertical-align: top; /* 2 */
}
/* ==========================================================================
Tables ========================================================================== */
/**
* Remove most spacing between table cells. */
table {
border-collapse: collapse; border-spacing: 0;
}
html, body { color: #111; background-color: transparent; width: 100%; height: 100%; margin: 0; padding: 0; display:block; line-height:normal;
}
h1 { font-weight:bold; font-size:52px; margin:0; text-transform:uppercase; font-family: 'Lato', sans-serif; font-weight:900; text-align:center; /*font-family: "Courier New", Courier, "Lucida Sans Typewriter", "Lucida Typewriter", monospace;*/ } h2 { font-weight:bold; font-size:24px; text-transform:uppercase; font-family: 'Lato', sans-serif; font-weight:900; /*font-family: "Courier New", Courier, "Lucida Sans Typewriter", "Lucida Typewriter", monospace;*/ } p { font-family: 'Lato', sans-serif; /*font-family: "Courier New", Courier, "Lucida Sans Typewriter", "Lucida Typewriter", monospace;*/ } img {margin:10px;}
.firstHeading { display:none;}
- content {border:none !important; line-height:normal !important;}
h1, h2, h3, h4 {border:none !important;}
- content, #gloabalWrapper {position:static !important;}
- globalWrapper {padding-top:100vh;}
- intro {
background: url(
) no-repeat center;
background-size:cover;
height:100vh;
width:100%;
display:block;
position:absolute;
top:0;
left:0;
text-align:center;
padding:7%;
box-sizing:border-box;
-moz-box-sizing:border-box;
-ms-box-sizing:border-box;
-webkit-box-sizing:border-box;
}
- intro p {padding: 10px 70px 10px 70px; background-color:rgba(255,255,255,0.7);}
</style>
</head>
Star-shaped peptides are a promising biomaterial being proposed for use in nanomedicine. While star peptides have conventionally been synthesised in vitro, the University of Melbourne iGEM team aims to use the peptide-synthesis machinery of E. coli to produce peptides in vivo. Star peptide precursors will be expressed as heterologous proteins in E. coli. Further processing using both the protein folding enzymes of E. coli and simple in vitro chemical synthesis techniques will yield star peptides. The products will be designed such that the arms of the stars may be functionalised with peptides, proteins, and other biomacromolecules. Thus, the project will develop a novel and powerful platform technology for the synthesis of new biomaterials. The technology developed may be readily applied in a variety of biomedical contexts, including drug delivery, infection control and cancer treatment.
