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Team:Rutgers/main.html
From 2014.igem.org
The Next Step in DNA Synthesis
We believe de novo DNA Synthesis is missing out on a brilliant tool invented by biology that makes stringing nucleotides together extremely quickly and extremely efficiently. We currently use organic solvents and reactive amidites to achieve synthesis, but it may be prudent to begin investigating natural, aqueous environments for synthesis using enzymes evolved alongside nucleic acids for billions of years.
Students
Kenny Kostenbader Chem Eng |
Scott Lazaro Cell Bio & Neurosci |
Wilson Wong Mol Bio |
Jay Patel Chem Eng |
Diego Barreto Biotechnology |
Wesley Okwemba Chem Eng |
Neil Patel Computer Eng |
Harsh Patel Cell Bio & Neurosci |
Gabriel Schimit Chem Eng |
Samantha Ashley Cell Bio & Neurosci |
Faculty
Sagar Khare P.I. |
Andrew Laudisi Lab Manager |
At the NEGEM Meetup (June 20)
(click to see full resolution)
Acknowledgements
Trilink Biotech - Acetylated Nucleotides for free
Dr Jones - synthesis & characterization (Ac2O + LC/MS)
Dr Williams - synthesis & characterization (AcCl + NMR)
Arun Nayar - lab training
BU's NEGEM Meetup - presented and learned a lot from others (see pictures below)
