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Team:Missouri Miners/Parts
From 2014.igem.org
Parts
Part PARTNUMBER is the isolated hmp gene from Escherichia Coli, and produces a protein, dihydropteridine reductase, which reduces nitric oxide to nitrate. Synthesis of its product is elevated in response to nitrite or nitric oxide through transcriptional regulation.
Part PARTNUMBER encodes a catalyst for the reduction of nitric oxide, flavorubredoxin oxidoreductase.
Cruz-Ramos, H., Crack, J., Wu, G., Hughes, M. N., Scott, C., Thomson, A. J., ... & Poole, R. K. (2002). NO sensing by FNR: regulation of the Escherichia coli NO-detoxifying flavohaemoglobin, Hmp. The EMBO journal, 21(13), 3235-3244.
Gardner, P. R., Gardner, A. M., Martin, L. A., & Salzman, A. L. (1998). Nitric oxide dioxygenase: an enzymic function for flavohemoglobin. Proceedings of the National Academy of Sciences, 95(18), 10378-10383.
Hausladen, A., Gow, A. J., & Stamler, J. S. (1998). Nitrosative stress: metabolic pathway involving the flavohemoglobin. Proceedings of the National Academy of Sciences, 95(24), 14100-14105.
Gardner, A. M., Helmick, R. A., & Gardner, P. R. (2002). Flavorubredoxin, an inducible catalyst for nitric oxide reduction and detoxification in Escherichia coli. Journal of Biological Chemistry, 277(10), 8172-8177.
Gomes, C. M., Giuffrè, A., Forte, E., Vicente, J. B., Saraiva, L. M., Brunori, M., & Teixeira, M. (2002). A novel type of nitric-oxide reductase Escherichia coli flavorubredoxin. Journal of Biological Chemistry, 277(28), 25273-25276.
Hmp fused nitric oxide dioxygenase/dihydropteridine reductase 2. (n.d.). Retrieved from http://www.ncbi.nlm.nih.gov/gene/947018
NorV anaerobic nitric oxide reductase flavorubredoxin. (n.d.). Retrieved from http://www.ncbi.nlm.nih.gov/gene/948979
