Team:ETH Zurich/expresults/rr

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Riboregulators

As many former iGEM teams have encountered basal expression (leakiness) of their genes of interest (ref ETH2013, Groningen2012 amongst others), we decided to investigate this severe obstacle. We started looking into the available literature and found with riboregultors a promising approach to challenge the issue of leakiness. In addition, we chose this approach, to further investigate and characterize such regulators in combination with cell-to-cell communication.