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Welcome to the Wiki of Team Tuebingen!

For this year's iGEM competition we have set out to create a viable system for the conversion of any blood type to the emergency blood type O using enzymes that are able to cut off the blood type antigens corresponding to blood types A, B and AB.

In order to prevent the mixing of the bacterial enzymes with donor blood we wanted to immobilise the enzymes on an activated glass matrix by attaching a so called N-intein to the enzymes and fusing the C-intein (a short oligopeptide) to the matrix.

Have a look around our wiki to find out more about the reasons why we wanted to pursue this project, the enzymes we have used for our system, and the intein we have decided to use for immobilisation-purposes! Of course, iGEM would not be the same without activities engaging the general public - find out, what we have planned this year.

Sponsors

We want to warmly thank the following sponsors of our iGEM2014 project (in no particular order):