Team:BYU Provo/Notebook/Biofilm/febapr
From 2014.igem.org
BYU 2014 Notebook |
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14 February 2014
We worked on some preliminary research regarding the biofilm aspect of our project idea. A good potential gene to look into is DispersinB which last year's BYU iGem team worked with some, so we can talk to team members from last year regarding that. Below are links for papers worth looking into more. (JB)
http://www.ncbi.nlm.nih.gov/pubmed/23103508
http://www.uniprot.org/citations/12896987
http://www.nlm.nih.gov/medlineplus/ency/article/000679.htm
19 February 2014
Today we read some more on the biofilm being formed in activated sludge processors like the one in Park City, UT. We are searching for different enzymes that could be utilized to break down the biofilm buildup found in these types of places. (JB)
11 March 2014
We emailed BYU's iGem team from last year which had done some work on biofilm degradation with alpha amylase and dispersin B. They gave us some good papers to look into regarding this aspect of our project. Another gene we have been looking into is Aiia, which is a quorum sensing blocker, which would be helpful in preventing aggregation of bacteria into biofilms. (JB)