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Team:Groningen/Template/MODULE/Project/secretion/part4
From 2014.igem.org
The construct
In order to synchronize the secretion of infection preventing molecules with the detection of the certain pathogens, a few conditions must been set.
- The construct should be regulated through detection.
- It must secrete DspB when L. lactis senses both P. aeruginosa and S. aureus
- It must secrete Aiia when it detect P. aeruginosa
- It must secrete Nisin when it detects S. aureus
After designing the systems, two constructs came out:
The anti-Pseudomonas aeruginosa system:
The anti-staphylococcus aureus secretion system:
Figure 6:
The DspB and AiiA construct
Figure 7:
The DspB and nisin construct
