Team:Gaston Day School/Modeling
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Isobutanol Pathway
Isobutanol Pathway
The figure above shows the native Isobutanol production pathway in E. coli. The figure is from Figure 1 in Atsumi, S., Hanai, T., and Liao, J.C., (2008). Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451(3):86.
Isobutanol Production Pathway
Isobutanol Production Pathway
Figure 2 shows the isobutanol production pathway in greater detail. This figure is from figure 1 in Atsumi, S., Wu, T., Eckl, E., Hawkins, S., Buelter, T., & Liao, J. (2009). Engineering the Isobutanol Biosynthetic Pathway in Escherichia Coli by Comparison of Three Aldehyde Reductase/Alcohol Dehydrogenase Genes. Appl Microbiol Biotechnol (2010) 85.651-657.
Mechanism for GlmY and GlmZ Actvity