Hi, we are Tsinghua TeamTeam Tsinghua and we are participating 2014 iGEM competitionin iGEM 2014. We are working on a gene therapy for Type 1 Diabetes Mellitus (T1DM).
T1DM results from the autoimmune destruction of insulin-producing beta cells in the pancreas. We aim to convert somatic cells into insulin-producing cells regulated by blood glucose, and eliminate the need for constant insulin therapy.
We use Adeno-associated viral (AAV) vectors to introduce genes, which has proven to be safe… Well, that’s a whole other story, want to know more?
Let’s hear it!
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