"
Team:UT-Tokyo
From 2014.igem.org
Pineappler (Talk | contribs) |
Pineappler (Talk | contribs) |
||
| Line 11: | Line 11: | ||
<div id="team"><img src="https://static.igem.org/mediawiki/2014/1/1e/Teamname.png"></div> | <div id="team"><img src="https://static.igem.org/mediawiki/2014/1/1e/Teamname.png"></div> | ||
<div id="index_navi"> | <div id="index_navi"> | ||
| - | <ul | + | <ul> |
<li><img src="https://static.igem.org/mediawiki/2014/7/7e/Toplink_projectoff.png"></li> | <li><img src="https://static.igem.org/mediawiki/2014/7/7e/Toplink_projectoff.png"></li> | ||
<li><img src="https://static.igem.org/mediawiki/2014/4/41/Toplink_resultoff.png"></li> | <li><img src="https://static.igem.org/mediawiki/2014/4/41/Toplink_resultoff.png"></li> | ||
Revision as of 07:01, 14 August 2014
Project Description
In the field of synthetic biology, Genetic memory devices have been constructed and applied widely from Biocomputing to biomedical technologies as a crucial component. Such memory devices include a cellular counter; a fundamental device which memorizes the number of induction events. Recent efforts have resulted in a cellular counter that can count up to three events. However, this counter cannot be reset to its initial state. Here, we propose a resettable cellular counter called “sigma recounter”. This counter utilizes the regulation system of sigma factor and anti-sigma factor as the key of its resetting mechanism. In this system a set of sigma factors are designed to update and maintain a count that responds to each inducted event. By the other stimulus, the system initiates a genetic circuit that can express a suitable set of anti-sigma factors and erases the existing memory, which will enable our device to restart the count from any state.
