Team:Oxford/biopolymer containment
From 2014.igem.org
(Difference between revisions)
Line 93: | Line 93: | ||
<br><br> | <br><br> | ||
- | For this system and others of its type, it is highly valuable to maximise local substrate concentration to the bacteria within the viable range of toxicity, especially | + | For this system and others of its type, it is highly valuable to maximise local substrate concentration to the bacteria within the viable range of toxicity, especially as the viable concentration range to the strain remains a limitation to the breakdown rate (directly or indirectly). |
<br><br> | <br><br> | ||
In our case, the diffusion-limiting polymer chosen was cellulose acetate (as its synthesis from cellulose is straightforward and safe) for which we modeled diffusion data for variable polymer thickness (see below). Acylation stoichiometry or even polymer type entirely, polymer density and methods of bead coating are among many variables that can be further researched and optimised for desirable diffusion coefficients. This means our biopolymer beads can be adapted to restrict diffusion of a wide range of substrates. | In our case, the diffusion-limiting polymer chosen was cellulose acetate (as its synthesis from cellulose is straightforward and safe) for which we modeled diffusion data for variable polymer thickness (see below). Acylation stoichiometry or even polymer type entirely, polymer density and methods of bead coating are among many variables that can be further researched and optimised for desirable diffusion coefficients. This means our biopolymer beads can be adapted to restrict diffusion of a wide range of substrates. |
Revision as of 02:25, 18 October 2014