Talk:Team:UMayor-Chile/Modeling

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<h1 >WELCOME TO iGEM 2014! </h1>
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      <div class="gwd-div-613s"><span class="gwd-span-29s7">The Cystic fibrosis</span>
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      <div class="gwd-div-r143"><span class="gwd-span-w7i9">(CF)</span>
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      <p class="MsoNormal"><span lang="EN-US"><span class="gwd-span-qyko">70,000
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people with CF worldwide, a lifespan depending of the resources (in USA the
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lifespan it’s about 40 years old, while in Chile the average lifespan it’s
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about 18 years old)</span>
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      <header><span class="gwd-span-dpni"><span class="gwd-span-oil2">Scene from Patient Assistance Resource Center video (Youtube). Cystic Fibrosis Foundation.</span></span>
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      <div class=""><span class="gwd-span-18v6">It’s a disease caused by the expression of a deficient transmembrane protein called CFTR. This affects different kind of cells, mainly the epithelial cells from the airway and pancreas, causing the production of a defective mucus.</span>
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      <div class=""><span class="gwd-span-28a8">&nbsp;In the lungs, this defective mucus leads that several opportunistic pathogens enter to the lower airway and initiate an infection, with a consecutively progressive lung dysfunction.</span>
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<a href="https://2014.igem.org/Team:UMayor-Chile"style="color:#000000">Home </a> </td>
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        <p class="MsoNormal"><span lang="EN-US" class="gwd-span-1esd">One of the
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main pathogens found in an infection of the lungs are the Pseudomonas
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aeruginosa. When it colonize the airway, initiates the production of biofilm, a
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barrier that protect it of a lot of antimicrobial substances and gave best environment
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for it develop.<o:p></o:p></span>
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<a href="https://2014.igem.org/Team:UMayor-Chile/Team"style="color:#000000"> Team </a> </td>
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        <p class="MsoNormal"><span lang="EN-US"><span class="gwd-span-4ix6">&nbsp;The actual treatments for controlling the symptoms
 +
consist in maintain controlled the pathogens, clear the airway of the sticky
 +
mucus, administrate complementary enzymes and regulate the function of the CFTR
 +
channel.&nbsp;</span>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=UMayor-Chile"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:UMayor-Chile/Project"style="color:#000000"> Project</a></td>
 
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<a href="https://2014.igem.org/Team:UMayor-Chile/Modeling"style="color:#000000"> Modeling</a></td>
 
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<a href="https://2014.igem.org/Team:UMayor-Chile/Attributions"style="color:#000000"> Attributions </a></td>
 
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<p>If you choose to create a model during your project, please write about it here. Modeling is not an essential part of iGEM, but we encourage any and all teams to model some aspect of their project. See previous "Best Model" awards for more information.</p>
 
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Revision as of 22:38, 17 October 2014



asd2
The Cystic fibrosis
(CF)

70,000 people with CF worldwide, a lifespan depending of the resources (in USA the lifespan it’s about 40 years old, while in Chile the average lifespan it’s about 18 years old)

Scene from Patient Assistance Resource Center video (Youtube). Cystic Fibrosis Foundation.
It’s a disease caused by the expression of a deficient transmembrane protein called CFTR. This affects different kind of cells, mainly the epithelial cells from the airway and pancreas, causing the production of a defective mucus.

 In the lungs, this defective mucus leads that several opportunistic pathogens enter to the lower airway and initiate an infection, with a consecutively progressive lung dysfunction.

One of the main pathogens found in an infection of the lungs are the Pseudomonas aeruginosa. When it colonize the airway, initiates the production of biofilm, a barrier that protect it of a lot of antimicrobial substances and gave best environment for it develop.

 The actual treatments for controlling the symptoms consist in maintain controlled the pathogens, clear the airway of the sticky mucus, administrate complementary enzymes and regulate the function of the CFTR channel. 

Retrieved from "http://2014.igem.org/Talk:Team:UMayor-Chile/Modeling"