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Team:Groningen/Template/MODULE/project/bandage/general1
From 2014.igem.org
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Measurements | Measurements | ||
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We want to add a color system which shows whether it's <i>S. aureus</i> or <i>P. aeruginosa</i> which is infecting the wound. Preferably this will activate as soon as the first bacteria is in sight. There is work done with GFP, this could be combined with RFP as well | We want to add a color system which shows whether it's <i>S. aureus</i> or <i>P. aeruginosa</i> which is infecting the wound. Preferably this will activate as soon as the first bacteria is in sight. There is work done with GFP, this could be combined with RFP as well | ||
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Appearance | Appearance | ||
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Our bandage should be transparent. This way you can look through it and judge whether it should be changed or it can stay on for another day. Seeing through the bandage without having to remove it is one of the criteria for the burn wound center as well. | Our bandage should be transparent. This way you can look through it and judge whether it should be changed or it can stay on for another day. Seeing through the bandage without having to remove it is one of the criteria for the burn wound center as well. | ||
Of course the bandage should be as thin as possible. We're aiming at a maximum thickness of one centimeter, and preferably ever thinner. | Of course the bandage should be as thin as possible. We're aiming at a maximum thickness of one centimeter, and preferably ever thinner. | ||
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Safety | Safety | ||
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Revision as of 21:44, 17 October 2014
Measurements
We want to add a color system which shows whether it's S. aureus or P. aeruginosa which is infecting the wound. Preferably this will activate as soon as the first bacteria is in sight. There is work done with GFP, this could be combined with RFP as well
Appearance
Our bandage should be transparent. This way you can look through it and judge whether it should be changed or it can stay on for another day. Seeing through the bandage without having to remove it is one of the criteria for the burn wound center as well.
Of course the bandage should be as thin as possible. We're aiming at a maximum thickness of one centimeter, and preferably ever thinner.
Safety
We have to make sure our bacteria stays inside the gel. Although it's unlikely that L. lactis infects a human, when immuno-compromised this is a possible. We can make sure the bacteria can't leave the bandage by adjusting the pore-size of this gel. Another extra safety point is the usage of a bottom membrane. This is membrane with a pore-size of 0.2um to make sure our molecules can diffuse, but the bacteria are stuck.
Since we're aiming for hospital usage we'd think that after use this bandage should be autoclaved, after that thrown away in the normal waste.
Comfort & User friendliness
The bandage shouldn't stick, burn wounds are painful enough as is and we don't want to add to that. Another thing is how easy the bandage can be activated. This should be within 30 minutes and as easy as possible. Also one of the problems could be how thick the bandage is, it needs to be as thin as possible to be decent to wear.
We'd like to add a plastic mash inside the bandage, this way it can bend without breaking completely
