Team:Warwick/Parts/Aptazyme
From 2014.igem.org
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<h1> APTAZYME </h1> <br> <br>--> | <h1> APTAZYME </h1> <br> <br>--> | ||
<h2> Click <a href="https://2014.igem.org/Team:Warwick/Parts">here</a> to learn about our Aptazyme. </h2> | <h2> Click <a href="https://2014.igem.org/Team:Warwick/Parts">here</a> to learn about our Aptazyme. </h2> | ||
- | <p> | + | <p>An aptazyme is an allosteric ribozyme acting as a regulatory riboswitch. It self-splices in response to theophylline, a drug used to treat asthma and other chronic obstructive pulmonary diseases acting as a bronchodilator. This differs from caffeine by one methyl group and a nitrogen atom creating the structure seen below. This is not endogenous to the body therefore we used this element as a "kill switch" for our system.</p> |
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Revision as of 23:21, 16 October 2014
Click here to learn about our Aptazyme.
An aptazyme is an allosteric ribozyme acting as a regulatory riboswitch. It self-splices in response to theophylline, a drug used to treat asthma and other chronic obstructive pulmonary diseases acting as a bronchodilator. This differs from caffeine by one methyl group and a nitrogen atom creating the structure seen below. This is not endogenous to the body therefore we used this element as a "kill switch" for our system.