Team:Vanderbilt/Safety

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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Vanderbilt/Safety&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="https://2014.igem.org/Team:Vanderbilt"style="color:#CC9900">Home </a> <br>
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<a href="https://2014.igem.org/Team:Vanderbilt"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:Vanderbilt/Team"style="color:#CC9900"> Team </a> </br>
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<a href="https://2014.igem.org/Team:Vanderbilt/Team"style="color:#000000"> Team </a> </td>
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<a href="https://2014.igem.org/Team:Vanderbilt/Project"style="color:#CC9900"> Project</a><br>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Vanderbilt"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Vanderbilt/Parts"style="color:#CC9900"> Parts</a></br>
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<a href="https://2014.igem.org/Team:Vanderbilt/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:Vanderbilt/Safety"style=" color:#CC9900"> Safety </a></br>
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Although our project did not use any particularly hazardous materials and both model organisms are classified in the lowest risk group, we took the safety of all our members as a high priority. Before being permitted to enter the lab, all members were required to pass a series of online safety training courses through Vanderbilt's VandySafe system. During a separate safety training meeting, members were informed of the proper way to dispose all used lab materials, procedures to take in the event of an emergency, proper handling of certain potentially hazardous chemicals, and general safe lab equipment use for items like Bunsen burners. We modeled our safety training after suggestions made by Vanderbilt Environmental Health and Safety (VEHS).  
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<tr><td > <h3> Welcome! </h3></td>
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One area of extra concern is that the transformed E. coli strains used have antibiotic resistance genes against both ampicillin and kanamycin. If these organisms were to escape the lab environment, it is conceivable that these resistance genes could undergo lateral gene transfer. The spread of antibiotic resistance in this way is significant to considerations of public health. Aside from the number of laboratory precautions we had taken in terms of maintaining sterile technique and properly disposing of all possible biohazards, in the design of our project we noted that homologous recombination into yeast would greatly reduce the danger of resistance genes spreading to other organisms.
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<td > <h3> Timeline</h3></td>
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<p> Visit the <a href="https://2014.igem.org/Safety" >Safety Hub</a> to see this year's safety requirements. The Safety Hub is the central page for everything related to safety in iGEM. You can also go there to learn about general biosafety topics, and how to think about the future implications of your project.</p>
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Please use this page to write about anything related to safety in your project. <!--Be sure to talk about both
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<h3> Your Lab </h3>
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Image:Example2_Lab_1.png|The building our lab is in!
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Image:Example2_Lab_3.png|Team Member 3 doing an experiment
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Image:Example2_Lab_4.png|Working in biosafety cabinets
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<li> <b>Now :</b>  Read the <a href="https://2014.igem.org/Safety">Safety Hub </a> and learn about safety in iGEM. Ask questions by emailing safety at <i> igem DOT org </i>. </li>
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<li><b>Now - Jamboree:</b> Complete <b>Check-Ins</b> and receive approval before acquiring and using certain materials in your lab</li>
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<li><b>Now - Wiki Freeze:</b> Edit this Safety page to tell us about what you're doing</li>
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<li><b>June 9: </b>Submit the About Our Lab form.</li>
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<li><b>Let us know by June 25 </b>if you will need an extension on the Preliminary Version, or your Preliminary Version will be significantly incomplete.</li>
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<li><b>June 30: </b>Submit the Preliminary Version of the <b>Safety Form</b>.</li>
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<li><b>September 1:</b> Submit the Final Version of the Safety Form.</li>
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Revision as of 22:42, 16 October 2014

Home
Team
Project
Parts
Notebook
Safety
Attributions
Although our project did not use any particularly hazardous materials and both model organisms are classified in the lowest risk group, we took the safety of all our members as a high priority. Before being permitted to enter the lab, all members were required to pass a series of online safety training courses through Vanderbilt's VandySafe system. During a separate safety training meeting, members were informed of the proper way to dispose all used lab materials, procedures to take in the event of an emergency, proper handling of certain potentially hazardous chemicals, and general safe lab equipment use for items like Bunsen burners. We modeled our safety training after suggestions made by Vanderbilt Environmental Health and Safety (VEHS).

One area of extra concern is that the transformed E. coli strains used have antibiotic resistance genes against both ampicillin and kanamycin. If these organisms were to escape the lab environment, it is conceivable that these resistance genes could undergo lateral gene transfer. The spread of antibiotic resistance in this way is significant to considerations of public health. Aside from the number of laboratory precautions we had taken in terms of maintaining sterile technique and properly disposing of all possible biohazards, in the design of our project we noted that homologous recombination into yeast would greatly reduce the danger of resistance genes spreading to other organisms.