Team:York/Cake

From 2014.igem.org

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<h1>Social sustainability</h1>
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<p>“GMO” has become something of a taboo phrase due to associations with “frankenfoods”.  An important part of being able to implement a project is having is become accepted by society. In order to tackle some of the social taboos about synthetic biology, we tried to spread interest, enthusiasm and education about our project.</p>
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<p>One of the ways we did this was to go into primary schools to educate children about synthetic biology. Members went into Victor Valcovici primary school in Galati, Romania to talk to children ages 6-9 about the use of bacteria and synthetic biology. We talked about the way genetically modified bacteria can be used to solve problems and had the children design their own “superhero bacteria”.  It was great to see the children getting so enthusiastic about science and to see their ingenious approaches to solving problem with our team-made iGEM kit activity packs.</p>
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<h1>Sustainability</h1>
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<h2>Victor Valcovici primary school</h2>
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<p>As we are aware of the controversial nature of our project, and GMOs in general, we decided to develop surveys on the topic of ethics, safety and sustainability in this field. Our aim was to find out what the main causes were for discouraging the use of GMOs and to find ways to make the public more open towards our project, as well as towards similar initiatives. We thought that a good way to do this would be to dispel some of the myths surrounding genetically engineered organisms, as well as educate the public regarding the science behind GMOs and the benefits that they can bring.</p>
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<p>Define: <b>Sustainable</b><br>
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Line breaks: <i>sus ¦ tain | able</i><br>
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ADJECTIVE: Able to be maintained at a certain rate or level<br></p>
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<p>The nature of democracy is one of fast but short-term improvement as policy makers have only a matter of a few years in which to prove themselves. This is reflective of human nature: we crave instant gratification at the cost of long-term improvement. However, today more than ever before it is clear how powerfully our actions impact our future. We need to build a more sustainable society.
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<p>We started by organising workshops and presentations in schools, for students with ages ranging from 6 to 18 years old. The workshops were adapted for the age of the students, with those aimed at primary school students being based on games and hands-on activities, while the ones for older students were more factual and detailed. We organised a workshop on synthetic biology at Richard Huish College in Somerset, that presented the students, aged 16 to 18, with the case study for one of the projects we were working on at the time. The students were made aware of the steps that we went through, including choosing a suitable project, securing funding and explaining our work and ideas to academics.</p>
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Our project aims to improve environmental sustainability of important industry by making the processes they use less environmentally damaging in the long run.
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However, part of what makes planning every project so challenging is that to be truly sustainable, it must be sustainable in every aspect. This is why our human practices are so important.</p>
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<h2>Cadmium in Global Waters</h2>
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<p>Cadmium in natural waters exists as either free/aquated cation (Cd<sup>2+</sup>/CdOH<sup>+</sup>)<sup>[1]</sup>  this is due to the competition of organic binding resulting in aluminium causing the almost complete displacement of cadmium.</p>
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<p>A large amount of cadmium pollution in water ways is due to either industrial waste or fertilizers produced from phosphate ores. In unpolluted natural waters the cadmium concentrations are usually below 1μg/l<sup>[2]</sup> however the maximum level ever recorded was in Rio Rimao in Peru at 100μg/l<sup>[3]</sup>.  The WHO have set the guideline level of cadmium in global drinking waters as 3μg/l<sup>[4]</sup> In 2007 UNEP stated these would be the parameters set for water quality as a global index<sup>[5]</sup>.
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<h3>References</h3><ol>
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<li>Posselt, H. S., Weber, W. J., (1974) Environmentla chemistry of Cd in aqueous systems. In. Rubin, A. J. (ed) Aqueous environmental chemistry of metals. Ann Arbor Science Publ. Inc., Ann Arbor, Michigan, p 255-289</li>
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<li>Friberg L, Nordberg GF, Vouk VB, eds. (1986) Handbook of the toxicology of metals.Vol. II. Amsterdam, Elsevier, pp. 130–184.</li>
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<li>WHO/UNEP (1989) GEMS — Global fresh water quality Published on behalf of the World Health Organization/United Nations Environment Programme. Oxford, Blackwell Reference. </li>
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<li>WHO. (2004.) Guidelines for Drinking-water Quality. Third Edition Volume1:Recommendations. World Health Organisation, Geneva</li>
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<li>United nations environment programme global environment monitoring system (GEMS)/ water programme (2007) Global drinking water quality index development and sensitivity analysis report. Burlington p 7.</li></ol></p>
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<h2>Cadmium Contamination Effects on Humans</h2>
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<p>The main issues with cadmium getting into waterways and food supplies are the affects that it will have on the people who ingest it. The effects of cadmium poisoning can be devastating as it is a known carcinogen and can consequently lead to death if ingested in large quantities. The other l effects of cadmium ingestion include:</p>
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  <li><p>Gastrointestinal effects such as nausea, vomiting, salivation, abdominal pain, cramps and diarrhoea<sup>[1]</sup></p></li>
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  <li><p>Anaemia due to the cadmium resulting in a lower level of iron intake in the gastrointestinal region, this is especially problematic if the affected individual already has low levels of iron intake in their diet<sup>[2]</sup></p></li>
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  <li><p>Kidney damage is a common symptom of cadmium toxicity which further leads to a decrease in production of vitamin D<sup>[3]</sup></p></li>
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  <li><p>Osteomalacis and osteoporosis both of which lead sufferers to have increased chance of bone fractures and lower bone density <sup>[4]</sup>. This may be as a result of the kidney damage giving way to decreased levels of vitamin D. <sup>[5]</sup></p></li>
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</ul>
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<h3>References</h3>
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<ol><p>
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  <li>Buckler, H. M., Smith, W. D., Rees, W. D. (1986) Self poisoning with oral cadmium chloride. Br Med J. 292(6535), 1559–1560.</li>
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  <li>Kagamimiori, S., Watanabe, M., Nakagawa, H., Okumura, Y. (1986) Case- control study on cardiovascular function in females with a history of heavy exposure to cadmium. Bull Environ Contam Toxicol. 36 (4), 484-490.</li>
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  <li>Arisawa, K., Nakano, A., Saito, H. et al. (2001) Mortality and cancer incidence among a population previously exposed to environmental cadmium. Int Arch Occup Environ Health. 74, 255-262.</li>
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  <li>Shigematsu, I. (1984) The epidemiological approach to cadmium pollution in Japan. Ann Acad Med Singapore. 13, 231-236.</li>
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  <li>Kido, T., Nogawa, K., Yamada, Y., et al (1989) Osteopenia in inhabitants with renal dysfunction induced by exposure to environmental cadmium. Int Arch Occup Environ Health. 61, 271-276.</li>
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</p></ol>
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<p>A member of our team visited the Victor Valcovici school in Galati, Romania, where children aged 6 to 10 participated in our workshop, entitled “Scientist for a Day”. They were given activity packs designed by the York iGEM team that included leaflets with information on bacteria and synthetic biology, educational games and a file with paper bacterial organelles that they could use to invent their own useful bacteria. The kids were very receptive and ingenious, their ideas – some more realistic than others – ranging from using fluorescent bacteria as a compass to creating scented bacteria that can be used in the production of bio-perfumes.</p>
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<img class="img-responsive img-max-650" src="https://static.igem.org/mediawiki/2014/2/2f/York_Victor.png">
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<h2>Richard Huish College, Taunton Somerset. (19th and 28th of March)</h2>
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<p>Richard Huish College, based in Taunton, is a sixth-form college providing education to 16-18 year olds. One of our team members visited the college and presented the our iGEM project to two groups of students. The students listened to a presentation about what iGEM was, why synthetic biology is important and how GMOs can be used commercially. The students were very keen to learn more about how synthetic biology works and how genetic engineering works.</p>
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<img class="img-responsive img-max-650" src="https://static.igem.org/mediawiki/2014/e/e6/York_Sixth.png">
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Revision as of 12:55, 16 October 2014

Team York 2014


Social sustainability

“GMO” has become something of a taboo phrase due to associations with “frankenfoods”. An important part of being able to implement a project is having is become accepted by society. In order to tackle some of the social taboos about synthetic biology, we tried to spread interest, enthusiasm and education about our project.

One of the ways we did this was to go into primary schools to educate children about synthetic biology. Members went into Victor Valcovici primary school in Galati, Romania to talk to children ages 6-9 about the use of bacteria and synthetic biology. We talked about the way genetically modified bacteria can be used to solve problems and had the children design their own “superhero bacteria”. It was great to see the children getting so enthusiastic about science and to see their ingenious approaches to solving problem with our team-made iGEM kit activity packs.

Victor Valcovici primary school

As we are aware of the controversial nature of our project, and GMOs in general, we decided to develop surveys on the topic of ethics, safety and sustainability in this field. Our aim was to find out what the main causes were for discouraging the use of GMOs and to find ways to make the public more open towards our project, as well as towards similar initiatives. We thought that a good way to do this would be to dispel some of the myths surrounding genetically engineered organisms, as well as educate the public regarding the science behind GMOs and the benefits that they can bring.

We started by organising workshops and presentations in schools, for students with ages ranging from 6 to 18 years old. The workshops were adapted for the age of the students, with those aimed at primary school students being based on games and hands-on activities, while the ones for older students were more factual and detailed. We organised a workshop on synthetic biology at Richard Huish College in Somerset, that presented the students, aged 16 to 18, with the case study for one of the projects we were working on at the time. The students were made aware of the steps that we went through, including choosing a suitable project, securing funding and explaining our work and ideas to academics.

A member of our team visited the Victor Valcovici school in Galati, Romania, where children aged 6 to 10 participated in our workshop, entitled “Scientist for a Day”. They were given activity packs designed by the York iGEM team that included leaflets with information on bacteria and synthetic biology, educational games and a file with paper bacterial organelles that they could use to invent their own useful bacteria. The kids were very receptive and ingenious, their ideas – some more realistic than others – ranging from using fluorescent bacteria as a compass to creating scented bacteria that can be used in the production of bio-perfumes.

Richard Huish College, Taunton Somerset. (19th and 28th of March)

Richard Huish College, based in Taunton, is a sixth-form college providing education to 16-18 year olds. One of our team members visited the college and presented the our iGEM project to two groups of students. The students listened to a presentation about what iGEM was, why synthetic biology is important and how GMOs can be used commercially. The students were very keen to learn more about how synthetic biology works and how genetic engineering works.