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Team:TCU Taiwan/Project
From 2014.igem.org
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<td align="center" width="15"> </td> | <td align="center" width="15"> </td> | ||
| - | <td align="center" width="250"><img src="https://static.igem.org/mediawiki/2014/e/e5/TCU-Part-logo.png" alt="Parts" width="128" height="128" onmouseover="Partsbox.color='#90B849'" onmouseout="Partsbox.color='#333'"/></td> | + | <td align="center" width="250" height="250"><img src="https://static.igem.org/mediawiki/2014/e/e5/TCU-Part-logo.png" alt="Parts" width="128" height="128" onmouseover="this.width=this.width*1.1;Partsbox.color='#90B849'" onmouseout="this.width=this.width/1.1;Partsbox.color='#333'"/></td> |
<td width="20"> </td> | <td width="20"> </td> | ||
<td align="center" width="250"><img src="https://static.igem.org/mediawiki/2014/4/4d/TCU_Blueprint-128.png" width="128" height="128" alt="System Design"/></td> | <td align="center" width="250"><img src="https://static.igem.org/mediawiki/2014/4/4d/TCU_Blueprint-128.png" width="128" height="128" alt="System Design"/></td> | ||
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| - | <td align="center"><img src="https://static.igem.org/mediawiki/2014/4/43/TCU_Gear-128.png" alt="CRISPR" width="128" height="128" /></td> | + | <td align="center" width="250" height="250"><img src="https://static.igem.org/mediawiki/2014/4/43/TCU_Gear-128.png" alt="CRISPR" width="128" height="128" /></td> |
<td> </td> | <td> </td> | ||
<td align="center"><img src="https://static.igem.org/mediawiki/2014/4/4a/TCU_1413400508_Briefcase.png" alt="Future Works" width="128" height="128" /></td> | <td align="center"><img src="https://static.igem.org/mediawiki/2014/4/4a/TCU_1413400508_Briefcase.png" alt="Future Works" width="128" height="128" /></td> | ||
Revision as of 08:00, 16 October 2014
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To access this, we use a special phagemid for phage display. The phagemid contains a additional phage replication origin. When helper phage (a phage whose own ori is knock-out) infection take place, phagemid can be packaged as genome for progeny. Since we put an antibiotic resistance gene targeting CRISPR system on our phagemid, this phage display can spread our CRISPR among bacterium nearby and remove their resistance efficiently. |
Trogene Horse is a new concept combining phage therapy with CRISPR, and this combination can solve both safety concern(phage therapy) and efficiency problem(CRISPR). We believe our project can deal with bacterial resistance problem on agriculture, and hope it can access on medicine one day. |
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Lost the way? Use it to help you if you're lost. |
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