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Team:Freiburg/Content/Project/Outlook
From 2014.igem.org
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<p>The AcCELLerator, while still in its infancy, might soon proof to be an asset in various areas. First of all, it can provide a powerful tool for the rapid generation of stable cell lines. The AcCELLerator can deliver different gene cargos ranging from orthogonal gene cargos, transcriptional activators or even modern genome engineering tools like the CRISPR/Cas system. In combination with a vector library comparable to a conventional DNA library it would be possible to express a certain gene within a couple of days. Such a library could accelerate basic research, especially when different genes have to be expressed with a high temporal and spatial resolution. </p> | <p>The AcCELLerator, while still in its infancy, might soon proof to be an asset in various areas. First of all, it can provide a powerful tool for the rapid generation of stable cell lines. The AcCELLerator can deliver different gene cargos ranging from orthogonal gene cargos, transcriptional activators or even modern genome engineering tools like the CRISPR/Cas system. In combination with a vector library comparable to a conventional DNA library it would be possible to express a certain gene within a couple of days. Such a library could accelerate basic research, especially when different genes have to be expressed with a high temporal and spatial resolution. </p> | ||
| - | <p>These properties are predistined to be used in the field of tissue engineering or synthetic production of biomaterials. In a tissue or biomaterial all cells have to express a distinct subset of genes; deficient gene expression would lead to abnormalities and cancer. Therefore a highly specific gene delivery is mandatory.</p | + | <p>These properties are predistined to be used in the field of tissue engineering or synthetic production of biomaterials. In a tissue or biomaterial all cells have to express a distinct subset of genes; deficient gene expression would lead to abnormalities and cancer. Therefore a highly specific gene delivery is mandatory.</p><p>As the potential applications are numerous and as it is not possible to optimize the system completely in the course of only one iGEM project, we encourage the community to use and improve the AcCELLerator!</p> |
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Revision as of 02:39, 14 October 2014
Outlook
The AcCELLerator, while still in its infancy, might soon proof to be an asset in various areas. First of all, it can provide a powerful tool for the rapid generation of stable cell lines. The AcCELLerator can deliver different gene cargos ranging from orthogonal gene cargos, transcriptional activators or even modern genome engineering tools like the CRISPR/Cas system. In combination with a vector library comparable to a conventional DNA library it would be possible to express a certain gene within a couple of days. Such a library could accelerate basic research, especially when different genes have to be expressed with a high temporal and spatial resolution.
These properties are predistined to be used in the field of tissue engineering or synthetic production of biomaterials. In a tissue or biomaterial all cells have to express a distinct subset of genes; deficient gene expression would lead to abnormalities and cancer. Therefore a highly specific gene delivery is mandatory.
As the potential applications are numerous and as it is not possible to optimize the system completely in the course of only one iGEM project, we encourage the community to use and improve the AcCELLerator!
