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Team:EPF Lausanne
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As for applied sciences, the BioPad could be used to deliver a cheap, fast, efficient, and accurate antibiotic screening system allowing researchers to easily quantify the effects of antibiotics on gram-negative bacteria. The BioPad project could also be the source of an "antibiotic complement" drug increasing the efficiency of pre-existing antibiotics. Moreover, the Biopad could provide a new approach to studying genes by allowing researchers to examine the relationship between genes and their corresponding activating signals. To learn more about the applications of our project click <a target="_blank" href="https://2014.igem.org/Team:EPF_Lausanne/Applications">here</a>.</p> | As for applied sciences, the BioPad could be used to deliver a cheap, fast, efficient, and accurate antibiotic screening system allowing researchers to easily quantify the effects of antibiotics on gram-negative bacteria. The BioPad project could also be the source of an "antibiotic complement" drug increasing the efficiency of pre-existing antibiotics. Moreover, the Biopad could provide a new approach to studying genes by allowing researchers to examine the relationship between genes and their corresponding activating signals. To learn more about the applications of our project click <a target="_blank" href="https://2014.igem.org/Team:EPF_Lausanne/Applications">here</a>.</p> | ||
Revision as of 10:06, 13 October 2014
Our project in a nutshell
Summary of our project
The 2014 EPFL iGEM team has been working on showing that biologically engineered organisms can detect and process signals quickly and efficiently. With this in mind, our team brought forward a novel idea: combining protein complementation techniques with biosensors to achieve fast spatiotemporal analysis of cell response to stimuli.
As a proof-of-concept, we aimed to develop the first BioPad: a biological trackpad made of a microfluidic chip, touch-responsive organisms and a signal detector. To make our organisms touch-sensitive, we engineering two stress-related pathways in E.Coli and S.Cerevisiae. In E.Coli, we engineered the Cpx Pathway - a two-component regulatory system responsive to envelope stress. In S.Cerevisiae, we modified the HOG Pathway - a MAPKK pathway responsive to osmotic stress. To learn more about the various components of our project, check out our overview section. If you are a judge, you might also be interested in our data page.
Envelope stress responsive bacteria
Can't touch this
Yeast
Discover how we took advantage of the HOG osmotic response pathway to create touch sensitive yeast strains! Learn more on how we implemented a split GFP and a split Luciferase in S.Cerevisiae leading to light emission when pressure is applied.
I.T
I like turtles.
Human practice
Are we human, or are we dancers ?
Safety
work in progress
MEET OUR TEAM
We are a group of 14 students from the faculties of Life, Biomechanical, and Computer Sciences, and are supervised by 2 EPFL professors, 1 Lecturer and 5 PhD students.
Sponsors
Copyright © iGEM EPFL 2014. All Rights Reserved
