Team:ULB-Brussels/Safety
From 2014.igem.org
Line 22: | Line 22: | ||
<section style="text-align: justify; margin: 100px"> | <section style="text-align: justify; margin: 100px"> | ||
<p><!--$\Large\mathcal{T}\normalsize$--> | <p><!--$\Large\mathcal{T}\normalsize$--> | ||
- | + | The main concerns raised by Mighty Coli depend more of the protein that we chose to produce than of Mighty Coli itself. However, Mighty Coli could compel an escaped recombinant bacterium to produce an industrial protein in the environment, when a bacterium without our system would quickly degenerate and stop producing the protein of interest. The risk seems thin, since such an overproducing bacterium would suffer from a clear competitive disadvantage in a wild environment.</p> | |
<section style="text-align: justify; margin: 20px"></section> | <section style="text-align: justify; margin: 20px"></section> | ||
Line 31: | Line 31: | ||
<section style="text-align: justify; margin: 20px"></section> | <section style="text-align: justify; margin: 20px"></section> | ||
<p>Rules of good handling should be respected for our system. Theses rules vary to one country to another. | <p>Rules of good handling should be respected for our system. Theses rules vary to one country to another. | ||
- | According to the Belgian Biosafety Server, Migthy coli is in risk class 1 because our construction cannot cause any disease in animals or plants or cause disorders in the environnement. But our construction has any feedback of safety in laboratory or in industry because it’s experimental. The risk class depends of the organism where the construction is inside but if it’s a organism of class 1 the laboratory must have different characteristic like: </p> | + | According to the Belgian Biosafety Server [1], Migthy coli is in risk class 1 because our construction cannot cause any disease in animals or plants or cause disorders in the environnement. But our construction has any feedback of safety in laboratory or in industry because it’s experimental. The risk class depends of the organism where the construction is inside but if it’s a organism of class 1 the laboratory must have different characteristic like: </p> |
<p>- A sink to wash and decontaminate the hands</p> | <p>- A sink to wash and decontaminate the hands</p> | ||
Line 56: | Line 56: | ||
<p>In conclusion, our system seems to be extremely safe and predictable, whose biggest danger consists of being used to produce a dangerous protein. This latter problem should be addressed on a case-by-case basis, by other institution than ours. Of course, our topical lab system is really safe, since it should only overproduce fluorescent proteins (GFP or RFP).</p> | <p>In conclusion, our system seems to be extremely safe and predictable, whose biggest danger consists of being used to produce a dangerous protein. This latter problem should be addressed on a case-by-case basis, by other institution than ours. Of course, our topical lab system is really safe, since it should only overproduce fluorescent proteins (GFP or RFP).</p> | ||
- | <p>Source : http://www.biosafety.be/CU/refdocs/SBB0306CU001FR.html</p> | + | <p>Source : [1] http://www.biosafety.be/CU/refdocs/SBB0306CU001FR.html</p> |
<!-- Gardons les pieds sur Terre: --> | <!-- Gardons les pieds sur Terre: --> | ||
<center><img src="https://static.igem.org/mediawiki/2014/4/42/ULB2014Safety.png"></center> | <center><img src="https://static.igem.org/mediawiki/2014/4/42/ULB2014Safety.png"></center> |
Revision as of 22:47, 10 October 2014
$~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\MyColi}{{\small Mighty\hspace{0.12cm}Coli}} \newcommand{\Stabi}{\small Stabi}$ $\newcommand{\EColi}{\small E.coli} \newcommand{\SCere}{\small S.cerevisae}\\[0cm] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ \newcommand{\PI}{\small PI}$ $\newcommand{\Igo}{\Large\mathcal{I}} \newcommand{\Tgo}{\Large\mathcal{T}} \newcommand{\Ogo}{\Large\mathcal{O}} ~$
|
---|