Team:uOttawa
From 2014.igem.org
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- | + | The mechanism behind pluripotency -- stem cells’ potential to differentiate into all different cell types-- has been a significant focus of modern research. In 2009, Sui Hang et al. theorized that pluripotency is controlled by a cascade of tri-stable switches, a type of genetic network motif that maintains three unique expression states simultaneously. This year, the uOttawa iGEM team is constructing iGEM’s first functional tri-stable switch based upon this theoretical premise in order to ascertain the potential for tri-stable switches to function as a differentiation mechanism. | |
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Revision as of 21:30, 15 August 2014
The mechanism behind pluripotency -- stem cells’ potential to differentiate into all different cell types-- has been a significant focus of modern research. In 2009, Sui Hang et al. theorized that pluripotency is controlled by a cascade of tri-stable switches, a type of genetic network motif that maintains three unique expression states simultaneously. This year, the uOttawa iGEM team is constructing iGEM’s first functional tri-stable switch based upon this theoretical premise in order to ascertain the potential for tri-stable switches to function as a differentiation mechanism. | ||||||||||||
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Requirements | ||||||||||||
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Tips | ||||||||||||
We are currently working on providing teams with some easy to use design templates.
For a full wiki list, you can visit iGEM 2013 web sites and iGEM 2012 web sites lists. |
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