Team:Toulouse/Project/Overview

From 2014.igem.org

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     <div class="Item" style="left :5%;">   
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             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Team" class="leaf">Our Team</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Team" class="leaf">Our Team</a></li>
             <li class="sub-nav-item" align="left"><a href="https://igem.org/Team.cgi?year=2014&team_name=Toulouse" class="leaf"> Official Team Profile </a></li>
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             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Project/Overview" class="leaf">Overview</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Project/Overview" class="leaf">Overview</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Project/Fixation" class="leaf">Fixation</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Project/Fixation" class="leaf">Fixation</a></li>
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             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Safety" class="leaf">Safety</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Safety" class="leaf">Safety</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Human_Practice/Ethique" class="leaf">Ethique</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Human_Practice/Ethique" class="leaf">Ethique</a></li>
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             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Notebook/Calendar" class="leaf">Calendar</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Notebook/Calendar" class="leaf">Calendar</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Notebook/Protocols" class="leaf">Protocols</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Notebook/Protocols" class="leaf">Protocols</a></li>
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             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Attributions" class="leaf">Attributions</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Attributions" class="leaf">Attributions</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Sponsors" class="leaf">Sponsors</a></li>
             <li class="sub-nav-item" align="left"><a href="https://2014.igem.org/Team:Toulouse/Sponsors" class="leaf">Sponsors</a></li>
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<!--Entrer votre texte ici -->
<!--Entrer votre texte ici -->
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<!--Titre-->
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<div class="Title">Overview: Save our trees with SubtiTree !</div>
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<br/>
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<br/>
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<img style="width:350px; float:right;" src="https://static.igem.org/mediawiki/2014/9/96/Canal1.png">
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<br/>
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<div class="Article">
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    <p>
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        Canker is one of the important infection caused by fungi and particularly affecting plane trees (Platanus sp.). Plane trees are widely present in Southern France and participated to the site gorgeousness. Today, the only treatment consists in preventive tree-cutting which has a huge cost and implies significant ecological troubles. Facing this emergency, our team offers an innovation alternative originated from synthetic biology.
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    </p>
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        Indeed, the aim of our project is to design an entophytic bacterium able to detect and target the pathogen in order to deliver different fungicides to save the tree from its invaders. This project limits the spreading of our engineered bacterium in the environment by considering ecological and ethical matters.
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    </p>
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<div class="Sub_title">Chimiotactism <a href="https://2014.igem.org/Team:Toulouse/Project/Chemotaxis" class ="Link">Show more</a></div>
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<table width="100%"><tr><td bgColor="#097F09" height="1px"></td> </tr></table>
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    <p>
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        First, the bacterium targets the fungi thanks to a chimiotactism module recognizing the soluble chitin monomers (N-acetyl-glucosamine).
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    </div>
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SubtiTree, a bacterium to save our trees
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Fungal diseases lead to major economic losses all over the world.
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Some pathogens trigger trachemycosis by disturbing the vascular system of the plant.
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Canker is one of these infections especially affecting plane trees (Platanus sp.). Plane trees are widely present in Southern France and particularly along the famous Canal du Midi, participating to the site gorgeousness.
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Today, the only treatment consists in preventive tree-cutting which has a huge cost and implies significant ecological troubles.
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Facing this emergency, our team offers an innovative alternative originated from synthetic biology.
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The aim of our project is to make an endophytic bacterium capable of detecting the pathogen, and targeting it in order to deliver different fungicides to save the tree from its invaders.
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Considering ecological and ethical matters, this project limits the spreading of our engineered bacterium in the environment.
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<div class="Sub_title">Fixation <a href="https://2014.igem.org/Team:Toulouse/Project/Fixation" class ="Link">Show more</a></div>
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    Then, SubtiTree binds onto the pathogen by a chimeric protein anchored on one side to the bacterium pepdidoglycan and on the other side to the fungal chitin-based wall.
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        To finish, our designed bacterium fights against the pathogen by setting up a powerful treatment based on the production of three different fungicides.
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Revision as of 15:49, 25 July 2014

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Overview: Save our trees with SubtiTree !



Canker is one of the important infection caused by fungi and particularly affecting plane trees (Platanus sp.). Plane trees are widely present in Southern France and participated to the site gorgeousness. Today, the only treatment consists in preventive tree-cutting which has a huge cost and implies significant ecological troubles. Facing this emergency, our team offers an innovation alternative originated from synthetic biology.

Indeed, the aim of our project is to design an entophytic bacterium able to detect and target the pathogen in order to deliver different fungicides to save the tree from its invaders. This project limits the spreading of our engineered bacterium in the environment by considering ecological and ethical matters.


Chimiotactism Show more

First, the bacterium targets the fungi thanks to a chimiotactism module recognizing the soluble chitin monomers (N-acetyl-glucosamine).


chimiotactism
Fixation Show more

Then, SubtiTree binds onto the pathogen by a chimeric protein anchored on one side to the bacterium pepdidoglycan and on the other side to the fungal chitin-based wall.

Biding
Fungicides Show more

To finish, our designed bacterium fights against the pathogen by setting up a powerful treatment based on the production of three different fungicides.

Fungicides
Spreading Show more

Text.

Spreading

Retrieved from "http://2014.igem.org/Team:Toulouse/Project/Overview"