Team:UCLA/Judging

From 2014.igem.org

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<p><b>Briefly describe the topics that you learned about in your safety training.</b></p>
 
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<p>Our safety training covered hazardous material storage and usage, biohazard usage practices, protective personal equipment, engineering and human safety controls, and in-depth properties of select hazards, such as peroxides and flammable compounds. The laboratory safety training requirements at UCLA can be found <a href = "http://policy.ucop.edu/doc/3500598/LabSafetyTraining">here</a> </p>
 
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<p><b>In your country, what are the regulations that govern biosafety in research laboratories? Please give a link to these regulations, or briefly describe them if you cannot give a link.</b></p>
 
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<p>In the USA, biosafety regulations are provided by the Center for Disease Control and Prevention (CDC) and the American Biological Safety Association (ABSA), and National Institute of Health (NIH)</p>
 
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<h2>Project Risks</h2>
 
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<p><b>Risks to the safety and health of team members, or other people working in the lab:</b></p>
 
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<p><i>E. coli</i> K12 strain does not pose a major safety risk to humans. <i>Nephila clavipes</i> silk, which is the expressed protein product in our project, does not pose a safety risk either. Nevertheless, skin contact and potential ingestion should be eliminated or minimized.</p>
 
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<p><b>Risks to the safety and health of the general public, particularly if any biological materials escaped from your lab:</b></p>
 
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<p>Spider silk does not pose any safety or health risk to the environment if released. <i>E. coli</i> may have unpredictable impacts on the local ecosystem if released, but this is unlikely.</p>
 
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<p><b>What measures are you taking to reduce these risks?</b></p>
 
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<p>We chose a very safe chassis organism to use, K12 <i>E.coli</i>. We are also wearing proper Personal Protective Equipment, such as lab coats, gloves, and safety glasses when handling biological materials. Additionally, any surfaces that have been potentially contaminated by bacterial species are thoroughly cleaned using ethanol and/or bleach. </p>
 
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<h2>Risks of Your Project in the Future</h2>
 
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<p><b>What new risks might arise from your project's growth? Also, what risks might arise if the knowledge you generate or the methods you develop became widely available?</b></p>
 
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<p>No safety risks would arise from the availability of our product or the knowledge of how to generate our product. There may be some impact to materials industries if the generation of genetically altered recombinant silk became commercially viable. For example, the natural silk industry may suffer if recombinant silk with altered properties became cheap. </p>
 
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<p><b>Does your project currently include any design features to reduce risks? Or, if you did all the future work to make your project grow into a popular product, would you plan to design any new features to minimize risks?</b></p>
 
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<p>We did not utilize any design features to mitigate risks. Expressing our protein causes the chassis bacteria to be metabolically disadvantaged, and so it would likely not survive in the wild.</p>
 
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Revision as of 01:22, 18 October 2014

iGEM UCLA





Judging

Bronze Medal Requirements

✔ Register the team and have a great summer.
✔ Successfully complete and submit the iGEM 2014 Judging Form.
Our judging form can be found here
✔ Create and share a Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.
✔ Plan to present a poster and talk at the iGEM Jamboree.
✔ Distinguish work done by others, including host labs, advisors, instructors, sponsors, professional website designers, artists, and commercial services.
All attributions can be found on our wiki.
✔ Document at least one new standard BioBrick part or device used in your project and submit this part to the iGEM Registry.
Thus far, we have submitted BBa_K1384000




Silver Medal Requirements

❏ Experimentally validate that at least one new BioBrick part or device of your own design and construction works as expected.
We will be validating our BioBrick soon! Stay tuned!
❏ Document the characterization of this part in the Main Page section of that Part's/Device's Registry entry.
We will update our part's documentation as soon as possible.
✔ Submit this new part to the iGEM Parts Registry.
We have submitted BBa_K1384000
❏ iGEM projects involve important questions beyond the bench, for example relating to (but not limited to) ethics, sustainability, social justice, safety, security, or intellectual property rights. Articulate at least one question encountered by your team, and describe how your team considered the(se) question(s) within your project. Include attributions to all experts and stakeholders consulted.




Gold Medal Requirements



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