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Team:Paris Bettencourt/Project/Odor Library
From 2014.igem.org
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<p class=text1>Synthetic enzymes can produce odors that humans experience directly, without special instruments. The banana and wintergreeen smell BioBricks are iGEM icons, and a favorite way to introduce genetic engineering. An expanded library of easy-to-use odor enzymes would take synthetic biology to new audiences for creativity, beauty and fun!</p></td> | <p class=text1>Synthetic enzymes can produce odors that humans experience directly, without special instruments. The banana and wintergreeen smell BioBricks are iGEM icons, and a favorite way to introduce genetic engineering. An expanded library of easy-to-use odor enzymes would take synthetic biology to new audiences for creativity, beauty and fun!</p></td> | ||
<td><b><center>AIMS</center></b></br><br> | <td><b><center>AIMS</center></b></br><br> | ||
| - | <p class=text1><left> | + | <p class=text1><left>We standardized and simplified existing smell-producing BioBricks for banana, wintergreen, lemon and rain. Also, we created new BioBricks for the aromas of popcorn and jasmine. We made an odor wheel made out of genetic odors that follow a standard organization so that the general public can play with odor genes.</left></li></ul></p></td> |
<td><b><center>ACHIEVEMENTS</center></b></br><br> | <td><b><center>ACHIEVEMENTS</center></b></br><br> | ||
<p class=text1><ul><li> Created BioBricks coding for sequences for different enzymes to nullify the bad odor produced by <i>E. coli.</i></li> <li>We produced the smells that compose the main odor categories perceived by humans.</li> <li>BioBricks submitted to be BioBrick registry:BBa_K1403003, BBa_K1403006, BBa_K1403009, BBa_K1403012, BBa_K1403017, BBa_K1403019</li> </p></td> | <p class=text1><ul><li> Created BioBricks coding for sequences for different enzymes to nullify the bad odor produced by <i>E. coli.</i></li> <li>We produced the smells that compose the main odor categories perceived by humans.</li> <li>BioBricks submitted to be BioBrick registry:BBa_K1403003, BBa_K1403006, BBa_K1403009, BBa_K1403012, BBa_K1403017, BBa_K1403019</li> </p></td> | ||
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<table id=tablelien> | <table id=tablelien> | ||
<tr> | <tr> | ||
| - | <td><a href="#part1"> | + | |
| - | <td><a href="#part2"> | + | <td><a href="#part1">Introduction</a></td> |
| - | <td><a href="#part3 | + | <td><a href="#part2">Results</a></td> |
| - | + | <td><a href="#part3">Methods</a></td> | |
</tr> | </tr> | ||
</table> | </table> | ||
<div id=part1 class=project> | <div id=part1 class=project> | ||
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| - | + | ||
| - | + | ||
<h6>Introduction</h6><br> | <h6>Introduction</h6><br> | ||
<p class=text1>There are complex relations among the stereochemistry of volatile compounds, their ratio within a particular mix, the amount of active olfactory receptors expressed in the smeller, as well as the distribution, and interaction of the different olfactory receptor neurons (ORNs). Odors spark neurochemical signals that are processed in different areas of the brain; they trigger complex cognitive processes that affect emotional responses such as motivation and memory. Although the precise molecular mechanisms behind odor perception have not been fully understood, there has been significant advance in the biosynthesis of organic volatile compounds using bacterial and fungal systems. </p> | <p class=text1>There are complex relations among the stereochemistry of volatile compounds, their ratio within a particular mix, the amount of active olfactory receptors expressed in the smeller, as well as the distribution, and interaction of the different olfactory receptor neurons (ORNs). Odors spark neurochemical signals that are processed in different areas of the brain; they trigger complex cognitive processes that affect emotional responses such as motivation and memory. Although the precise molecular mechanisms behind odor perception have not been fully understood, there has been significant advance in the biosynthesis of organic volatile compounds using bacterial and fungal systems. </p> | ||
Revision as of 01:55, 18 October 2014
Stop And Smell The Roses
Synthetic enzymes can produce odors that humans experience directly, without special instruments. The banana and wintergreeen smell BioBricks are iGEM icons, and a favorite way to introduce genetic engineering. An expanded library of easy-to-use odor enzymes would take synthetic biology to new audiences for creativity, beauty and fun! |
|
| Introduction | Results | Methods |
Introduction
There are complex relations among the stereochemistry of volatile compounds, their ratio within a particular mix, the amount of active olfactory receptors expressed in the smeller, as well as the distribution, and interaction of the different olfactory receptor neurons (ORNs). Odors spark neurochemical signals that are processed in different areas of the brain; they trigger complex cognitive processes that affect emotional responses such as motivation and memory. Although the precise molecular mechanisms behind odor perception have not been fully understood, there has been significant advance in the biosynthesis of organic volatile compounds using bacterial and fungal systems.
Results
Proper BioBrick characterization is needed before tinkering with expression levels; the possibility to change ribosomal binding sites according to the desired expression is included in our design. We would also like to develop auto-inducible smelly systems, as well as broaden the available tones in our palette.
Methods
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