Team:BGU Israel/Project1
From 2014.igem.org
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Revision as of 21:57, 17 October 2014
Western modern lifestyle brought us a lot of wonderful
innovations, but also many problems. Today, about 25% of the adult world
suffers from the Metabolic Syndrome. This syndrome is a cluster of
medical conditions, including: abdominal obesity, elevated blood
pressure, Insulin resistance, high blood triglycerides and more.
These medical conditions are interconnected and are a result of
complex metabolic pathways, meaning most traditional drugs used to treat
them have undesired side effects. We intend to utilize synthetic biology
in order to develop novel strategies for the treatment of metabolic
syndrome.
Realizing the complexity of the Metabolic Syndrome, we envisioned the
need for multiple treatments. Our Inner Doctor combines four novel
strategies, offering treatments based on synthetic biology, with each
strategy addresses a different aspect of the metabolic syndrome. Our
Intelligence Medication decreases insulin resistance in a tissue specific
manner; Aspiration Shift reduces non-adipose fat accumulation; Artificial
Exercise will increase the energy expenditure of the body; The Hormone
Workshop will have an overall positive metabolic influence.