Team:TCU Taiwan/Project

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         <td width="20">&nbsp;</td>
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         <td align="center" width="250"><img src="https://static.igem.org/mediawiki/2014/4/4d/TCU_Blueprint-128.png" width="128" height="128"  alt="System Design"/></td>
         <td align="center" width="250"><img src="https://static.igem.org/mediawiki/2014/4/4d/TCU_Blueprint-128.png" width="128" height="128"  alt="System Design"/></td>
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  <td style="background-color:#FFF2B5" height="20px"><font face="Trebuchet MS" size="7" color="#A66B38">Trogene Horse</font></td>
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  <td>&nbsp;</td>
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<font size="3" face="Verdana" color="#333"><p>To access this, we use a special <a href="http://en.wikipedia.org/wiki/Phagemid" target="_blank">phagemid</a>  for phage display. The phagemid contains a additional phage replication origin.  When helper phage (a phage whose own ori is knock-out) infection take place,  phagemid can be packaged as genome for progeny. Since we put an <a href="http://en.wikipedia.org/wiki/Antibiotic_resistance" target="_blank">antibiotic</a>  resistance gene targeting <a href="http://en.wikipedia.org/wiki/CRISPR" target="_blank">CRISPR</a> system on our phagemid, this phage display can  spread our CRISPR among bacterium nearby and remove their resistance  efficiently.</p></font>
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<font size="3" face="Verdana" color="#333"><p>Trogene Horse is a new concept combining  phage therapy with CRISPR, and this combination can solve both safety  concern(phage therapy) and efficiency problem(CRISPR). We believe our project  can deal with bacterial resistance problem on agriculture, and hope it can  access on medicine one day.</p></font></td>
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<tr> <td> <h3 id="topic3">Topic 3</h3>  </td> </tr>
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Revision as of 08:01, 16 October 2014


 
Project
  
   
Trogene Horse  
Abstract
Topic 1
Topic 2
Topic 3
References
Abstract
   

To access this, we use a special phagemid for phage display. The phagemid contains a additional phage replication origin. When helper phage (a phage whose own ori is knock-out) infection take place, phagemid can be packaged as genome for progeny. Since we put an antibiotic resistance gene targeting CRISPR system on our phagemid, this phage display can spread our CRISPR among bacterium nearby and remove their resistance efficiently.

Trogene Horse is a new concept combining phage therapy with CRISPR, and this combination can solve both safety concern(phage therapy) and efficiency problem(CRISPR). We believe our project can deal with bacterial resistance problem on agriculture, and hope it can access on medicine one day.

Topic 1

 

 

Topic 2

 

Topic 3

 

References
Program
 
  Parts   System Design   M13 Phage  
             
  Parts   System Design   M13 Phage  
             
  CRISPR   Future Works   Human Pratics  
             
  CRISPR   Future Work   Human Pratics  
 
^


    
Team Members Project Parts Human Pratics Modeling Safety Notebook Attributions

Lost the way? Use it to help you if you're lost.

^


 
Project
  
   
Trogene Horse  
Abstract
Topic 1
Topic 2
Topic 3
References
Abstract
   

To access this, we use a special phagemid for phage display. The phagemid contains a additional phage replication origin. When helper phage (a phage whose own ori is knock-out) infection take place, phagemid can be packaged as genome for progeny. Since we put an antibiotic resistance gene targeting CRISPR system on our phagemid, this phage display can spread our CRISPR among bacterium nearby and remove their resistance efficiently.

Trogene Horse is a new concept combining phage therapy with CRISPR, and this combination can solve both safety concern(phage therapy) and efficiency problem(CRISPR). We believe our project can deal with bacterial resistance problem on agriculture, and hope it can access on medicine one day.

Topic 1

 

 

Topic 2

 

Topic 3

 

References
Program
 
  Retrieved from "http://2014.igem.org/Team:TCU_Taiwan/Project"