Team:NJAU China

From 2014.igem.org

(Difference between revisions)
Line 298: Line 298:
     <!-- /.carousel -->
     <!-- /.carousel -->
</div>
</div>
-
<!-- Marketing messaging and featurettes
 
-
    ================================================== -->
 
-
<!-- Wrap the rest of the page in another container to center all the content. -->
 
-
 
-
<div class="container marketing">
 
-
 
-
    <!-- START THE FEATURETTES -->
 
-
 
-
    <hr class="featurette-divider">
 
-
    <div class="row featurette">
 
-
        <div class="col-md-7">
 
-
            <h2 class="featurette-heading">First featurette heading. <span
 
-
                    class="text-muted">It'll blow your mind.</span></h2>
 
-
 
-
            <p class="lead">Donec ullamcorper nulla non metus auctor fringilla. Vestibulum id ligula porta felis euismod
 
-
                semper. Praesent commodo cursus magna, vel scelerisque nisl consectetur. Fusce dapibus, tellus ac cursus
 
-
                commodo.</p>
 
-
        </div>
 
-
        <div class="col-md-5"><img src="https://static.igem.org/mediawiki/2014/1/10/Njau_home_1.jpg"
 
-
                                  alt="Generic placeholder image" class="featurette-image img-responsive"></div>
 
-
    </div>
 
-
    <hr class="featurette-divider">
 
-
    <div class="row featurette">
 
-
        <div class="col-md-5"><img src="https://static.igem.org/mediawiki/2014/8/8a/Njau_home_2.jpg"
 
-
                                  alt="Generic placeholder image" class="featurette-image img-responsive"></div>
 
-
        <div class="col-md-7">
 
-
            <h2 class="featurette-heading">Oh yeah, it's that good. <span class="text-muted">See for yourself.</span>
 
-
            </h2>
 
-
 
-
            <p class="lead">Donec ullamcorper nulla non metus auctor fringilla. Vestibulum id ligula porta felis euismod
 
-
                semper. Praesent commodo cursus magna, vel scelerisque nisl consectetur. Fusce dapibus, tellus ac cursus
 
-
                commodo.</p>
 
-
        </div>
 
-
    </div>
 
-
    <hr class="featurette-divider">
 
-
    <div class="row featurette">
 
-
        <div class="col-md-7">
 
-
            <h2 class="featurette-heading">And lastly, this one. <span class="text-muted">Checkmate.</span></h2>
 
-
 
-
            <p class="lead">Donec ullamcorper nulla non metus auctor fringilla. Vestibulum id ligula porta felis euismod
 
-
                semper. Praesent commodo cursus magna, vel scelerisque nisl consectetur. Fusce dapibus, tellus ac cursus
 
-
                commodo.</p>
 
-
        </div>
 
-
        <div class="col-md-5"><img src="https://static.igem.org/mediawiki/2014/1/1e/Njau_home_3.jpg"
 
-
                                  alt="Generic placeholder image" class="featurette-image img-responsive"></div>
 
-
    </div>
 
-
    <hr class="featurette-divider">
 
     <!-- /END THE FEATURETTES -->
     <!-- /END THE FEATURETTES -->

Revision as of 16:05, 15 October 2014

Home

Abstract

As copper is an essential element for industry, low concentration of it can do harm to many creatures. Whereas, the Escherichia coli has high tolerance for copper through specific systems. There are copA promoter、marO（operator of mar locus）、cueO promoter existed in E.Coli, both are directly or indirectly regulated by copper ions. The most sensitive and effective would be chosen to trigger the sequential reactions. Glutathione is an intracellular redox-active tripeptide thiol which can effectively detoxify the metal ions by chelation. Glutathione can be synthesized by GshF, an enzyme derived from Streptococcus thermophilus, which can unifies both necessary reactions in one platform. In addition, we also utilize sgRNA-dCas9 system to enhance the efficiency of chelate cupric and cuprous by repressing the expression of copA. Finally, an automatically and efficiently copper-preventing guard are hoped to built.

Retrieved from "http://2014.igem.org/Team:NJAU_China"