Team:EPF Lausanne
From 2014.igem.org
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As for applied sciences, the BioPad could be used to deliver a cheap, fast, efficient, and accurate antibiotic screening system allowing researchers to easily quantify the effects of antibiotics on gram-negative bacteria. The BioPad project could also be the source of an "antibiotic complement" drug increasing the efficiency of pre-existing antibiotics. Moreover, the Biopad could provide a new approach to studying genes by allowing researchers to examine the relationship between genes and their corresponding activating signals. To learn more about the applications of our project click <a target="_blank" href="https://2014.igem.org/Team:EPF_Lausanne/Applications">here</a>.</p> | As for applied sciences, the BioPad could be used to deliver a cheap, fast, efficient, and accurate antibiotic screening system allowing researchers to easily quantify the effects of antibiotics on gram-negative bacteria. The BioPad project could also be the source of an "antibiotic complement" drug increasing the efficiency of pre-existing antibiotics. Moreover, the Biopad could provide a new approach to studying genes by allowing researchers to examine the relationship between genes and their corresponding activating signals. To learn more about the applications of our project click <a target="_blank" href="https://2014.igem.org/Team:EPF_Lausanne/Applications">here</a>.</p> |
Revision as of 10:06, 13 October 2014
Our project in a nutshell
Summary of our project
![EPFL_interaction_IFP_cartoon](https://static.igem.org/mediawiki/2014/0/0f/Interaction_test_11_cyan_white_bg_bigger.gif)
The 2014 EPFL iGEM team has been working on showing that biologically engineered organisms can detect and process signals quickly and efficiently. With this in mind, our team brought forward a novel idea: combining protein complementation techniques with biosensors to achieve fast spatiotemporal analysis of cell response to stimuli.
As a proof-of-concept, we aimed to develop the first BioPad: a biological trackpad made of a microfluidic chip, touch-responsive organisms and a signal detector. To make our organisms touch-sensitive, we engineering two stress-related pathways in E.Coli and S.Cerevisiae. In E.Coli, we engineered the Cpx Pathway - a two-component regulatory system responsive to envelope stress. In S.Cerevisiae, we modified the HOG Pathway - a MAPKK pathway responsive to osmotic stress. To learn more about the various components of our project, check out our overview section. If you are a judge, you might also be interested in our data page.
![touch bacteria](https://static.igem.org/mediawiki/2014/c/ce/Exp1_MM.png)
Envelope stress responsive bacteria
Can't touch this
![Yeast](https://static.igem.org/mediawiki/2014/b/b3/Beer.png)
Yeast
Discover how we took advantage of the HOG osmotic response pathway to create touch sensitive yeast strains! Learn more on how we implemented a split GFP and a split Luciferase in S.Cerevisiae leading to light emission when pressure is applied.
I.T
I like turtles.
![Human practice](https://static.igem.org/mediawiki/2014/1/15/Human_pract_blanc.png)
Human practice
Are we human, or are we dancers ?
![Safety](https://static.igem.org/mediawiki/2014/b/b3/Safety_box.png)
Safety
work in progress
MEET OUR TEAM
We are a group of 14 students from the faculties of Life, Biomechanical, and Computer Sciences, and are supervised by 2 EPFL professors, 1 Lecturer and 5 PhD students.
![the team's students](https://static.igem.org/mediawiki/2014/2/2c/Team_pic_sitting.jpg)